Melatonin for huntington disease (HD) gene carriers with HD-related sleep disturbance – a pilot study
Objective: To evaluate the efficacy of exogenous melatonin in improving sleep quality in Huntington disease (HD) gene carriers. Background: Various sleep disorders have been identified…The Quebec Parkinson Network (QPN): Interdisciplinary Collaboration in Parkinson’s Disease and Related Disorders Research.
Objective: By creating a participant registry, gathering information on participants, and ensuring appropriate data exchange with research groups, the QPN's primary goal is to increase…Improvements in Parkinson’s disease motor complications after treatment with opicapone: results from the OPTI-ON study
Objective: To describe motor complications as measured by the Movement Disorder Society-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) Part IV in participants from the Opicapone Treatment…Epigenetic clocks suggest accelerated ageing in isolated REM Sleep Behavior Disorder patients
Objective: To investigate biological aging in videopolysomnography (vPSG)-confirmed isolated REM Sleep Behavior Disorder (iRBD) patients and vPSG-negative controls, using DNA methylation-based epigenetic clocks. Background: Isolated…Supra-ON state freezing of gait: The unpredictable response to levodopa in Parkinson´s Disease
Objective: To discuss the therapeutic dilemma of freezing in supra ON Background: Freezing of gait (FOG) is a common manifestation of Parkinson's disease (PD), occurring…Subacute parkinsonism associated with Zic4 antibodies: a case report
Objective: Describe a case of subacute parkinsonism associated with isolated Zic4 antibodies. Background: Movement disorders are a common feature in autoimmune encephalitis and its presentation…Assessment of variation in α-synuclein seed amplification assay results in the PPMI cohort: Association with hyposmia
Objective: To understand molecular heterogeneity among Parkinson’s disease (PD) patients, and controls based on α-synuclein seed amplification assay (SAA) results. Background: α-synuclein seed amplification assay…Muscle functions on the movement timings and inhibition in Parkinson’s disease.
Objective: To assess the role of muscle strength, muscle tone and reflexes on the movement timings and inhibitory control in the subjects of Parkinson’s disease…Deep Brain Stimulation for Multiple Sclerosis Tremors: A Case Series
Objective: The objective of our study is to report the evidence on the effectiveness and safety of Deep Brain Stimulation (DBS) in managing upper extremity…Machine Learning Prediction of Gait Dysfunction from DTI Multi-Spectral Diffusion Weighted Imaging ROIs
Objective: To compare the performance of various machine learning techniques, including LDA, k-NN, SVM, MLP, Long Short-Term Memory (LSTM), Gradient Boosting Machines (GBM), Random Forest,…
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