Effects of ankle dorsiflexion training on anticipatory postural adjustments during gait initiation of patients with Parkinson’s disease
Objective: The purpose of this study was to investigate whether ankle dorsiflexion training (ADT) for patients with Parkinson’s disease (PD) may improve anticipatory postural adjustments…An Open-Access Model for Parkinson’s Disease Progression
Objective: To model the progression of PD by developing a hidden Markov model which incorporates nonlinear effects of disease severity and medication on clinical scores.…Identifying a path to improve diagnostic delay and access to care for PSP, CBS, and MSA
Objective: To understand diagnosis and care experiences of patients and care partners living with progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy…A 20-year review of a Movement Disorders Database in Singapore
Objective: To conduct a 20-year review of the movement disorders (MD) clinical database in Singapore. Background: MDs contribute to a significant portion of chronic disease…MDS-UPDRS III Off Severity Level changes as a marker of DBS response
Objective: To determine the change in MDS-UPDRS III severity level after Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) in patients with Parkinson’s disease (PD) and evaluate…The prevalence of Parkinson’s disease in a predominantly rural area of North West England
Objective: To calculate the crude and age adjusted prevalence of Parkinson’s disease (PD) in North Cumbria. Background: Prevalence data give insight into disease cause and…Identification of pre-frailty in the elderly through serum metabolomics and its impact on Parkinson’s disease phenotype
Objective: We attempted to better characterize pre-frailty using serum metabolomics in a large cohort of elderly subjects without neurodegenerative diseases. Next, we sought to investigate…Preparing for a clinical trial: a run-in natural history study in POLR3A-associated spastic ataxia with intronic mutations amenable to splice-modulating therapeutic approaches
Objective: The aim of this study is the identification of progression and treatment response outcomes for POLR3A-associated spastic ataxia caused by the recurrent intronic c.1909+22G>A…Unilateral GPi DBS in Secondary Myoclonus-Dystonia Syndrome after Acute Disseminated Encephalomyelitis: A Case Report
Objective: To present a case of deep brain stimulation (DBS)-ameliorated myoclonus-dystonia syndrome secondary to acute disseminated encephalomyelitis (ADEM) and characterize fibers and circuits affected by…Access-PD – a ‘next generation’ registry to accelerate Parkinson’s disease research
Objective: To establish an integrated and fully remote registry for Parkinson’s disease (PD) in England, that leverages both electronic health records (EHR) and electronic patient-reported…
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