A network imaging biomarker of X-linked dystonia-parkinsonism
Objective: To characterize a metabolic brain network associated with X-linked dystonia-parkinsonism (XDP). Background: X-linked dystonia-parkinsonism (XDP, DYT/PARK-TAF1, Lubag) is an X-linked recessive movement disorder characterized…A rare case of PDE10A associated dystonia with bilateral striatal lesions
Objective: To describe an interesting and rare case of cervical dystonia associated with PDE10A mutation. Background: Dystonia is the third most prevalent movement disorder in…Gene-environment interactions for Parkinson’s disease
Objective: The aim of this study was to test for interactions between PD-related genetic and phenotypic traits in the 23andMe, Inc. research cohort. Background: Parkinson’s…Study protocol for the iMarkHD study in individuals with Huntington’s disease
Objective: To describe the study protocol for the iMarkHD study. Background: Huntington’s disease (HD) is still often defined by the onset of motor symptoms, inversely…Integrated safety analysis of BIA-28-6156 phase 1 clinical trials (a novel allosteric activator of beta-glucocerebrosidase)
Objective: To describe the safety profile and tolerability of BIA-28-6156 observed during phase 1 clinical trials. Background: BIA-28-6156 is a novel allosteric activator of beta-glucocerebrosidase…Microelectrode recording with subthalamic nuclei deep brain stimulation encompass neuro-electro physiological beta oscillations footmarks in Parkinson`s cardinal motor symptoms sub-types
Objective: To examine the behavioral-activity within sub bands of β-beta-oscillated local field potentials(‘LFP’) acquired through microelectrode recording(MER) from STN sub areas offer distinctive neuro-electro physiological…A Need for Improving the Diet Quality of Individuals with Parkinson’s Disease
Objective: This is a quality improvement project undertaken with an aim to evaluate the diet quality and adherence to the Mediterranean diet among individuals with…Movement disorders spectrum in CTNNB1-related neurodevelopmental disorders
Objective: To describe the phenomenology and clinical course of movement disorders in CTNNB1-related neurodevelopmental disorder (CTNNB1-NDD). Background: CTNNB1-NDD is a rare neurogenetic condition caused by…Dysphagia and dopaminergic neurodegeneration in Parkinson’s Disease
Objective: To evaluate the association between dysphagia and neurodegeneration of the putaminal dopaminergic system in people with early-stage treated with symptomatic therapy and advanced-stage Parkinson’s…Essential tremor suppression using a novel anti-tremor orthosis
Objective: Assess the efficacy of a novel anti-tremor orthosis in reducing hand and forearm tremor in patients with Essential Tremor in a clinical setting. Background:…
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