Epigenetic clock acceleration is linked to earlier onset and phenoconvertion of Rapid-eye-movement sleep behavior disorder
Objective: In the current study, we aim to evaluate whether Rapid-eye-movement sleep behavior disorder (RBD) age-at-onset and age-at-phenoconversion are associated with DNA methylation-age acceleration (DNAm-AA).…Exosomal α-synuclein in Multiple system atrophy and parkinson’s disease cause distinct synucleinopathies
Objective: In this study, we investigated the differences in exosomal α-syn between MSA and PD patients. Background: Parkinson's disease (PD) and multiple system atrophy (MSA)…Asymmetric synaptic density and glucose consumption in subjects with non-demented Parkinson’s Disease, as measured with [11C]UCB-J and [18F]FDG PET.
Objective: The objective of this study was to investigate asymmetric synaptic density and glucose consumption in moderate-stage non demented PD patients and the association between…Cortical thickness and global atrophy progression in Parkinson’s disease with probable RBD
Objective: To explore 3-year cortical thickness (CTh) and global atrophy progression in treated Parkinson’s disease (PD) with probable REM sleep behavior disorder (RBD). Background: Parkinson’s…Efficacy and safety of Mexiletine versus Placebo in patients with myotonia: A Systematic Review and Meta-analysis
Objective: We conducted this study to be the first systematic review and meta-analysis to investigate the efficacy and safety of mexiletine in the treatment of patients…Optimal topographic characteristics of focused ultrasound unilateral thalamotomy for tremor-dominant Parkinson´s disease
Objective: To define topography that correlates with tremor control after unilateral focused ultrasound (FUS) thalamotomy for tremor-dominant Parkinson´s Disease (TDPD). Background: Unilateral FUS thalamotomy of…Challenges in patient-physician communication during limited time appointments in Parkinson’s disease
Objective: Our aim is to analyze challenges in patient-physician communication during limited time appointments in Parkinson’s disease (PD). Background: Due to limited number of movement…Cell-specific MAPT gene expression is preserved in tau cytopathologies in Progressive Supranuclear Palsy
Objective: To systematically map and quantify MAPT expression in neurons, astrocytes and oligodendroglia across different brain regions to determine whether cell type and/or regional differences…Comparison of cognitive , affective and autonomic functions in parkinson’s disease patients with and without freezing of gait and its correlation with PET/CT
Objective: To study and compare the cognitive, affective and autonomic domains in Parkinson’s disease patients with and without freezing of gait and to correlate with…The effect of peptic ulcer disease on Parkinson’s disease
Objective: To compare patients with Parkinson’s disease (PD, PwP) with and without peptic ulcer disease (PUD) regarding cognition, psychiatric status, motor and non-motor symptoms, mobility,…
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