Longitudinal clinical and biomarker characteristics of non-manifest GBA1 N409S carriers: the PPMI cohort
Objective: To examine longitudinal change in clinical characteristics, dopamine transporter (DAT) imaging and biofluid biomarkers in GBA1 N409S non-manifesting carriers (NMCs) versus healthy controls (HCs)…Continuous estimation of Parkinson’s on-off states using wearable devices
Objective: Utilize passive, continuous data from mobile and wearable devices to estimate on-off states in Parkinson’s patients. Background: The Hauser motor diary is often used…Wilson disease: a single-center study from Tunisia
Objective: We aimed to describe different clinical and radiological presentations of WD and insist on the necessity of early diagnosis to ensure therapeutic efficiency. Background:…MR-guided focused ultrasound pallidothalamic tractotomy in non-tremor dominant (akinetic-rigid) Parkinson’s disease treatment
Objective: The study aims to show that unilateral MR-guided focused ultrasound (MRgFUS) treatment akinetic-rigid Parkinson's disease (PD) can be safe and effective. Background: Parkinson's disease…A Parkinson Shoe with Combined Plantar Pressure and Vibratory Stimulation in Parkinson’s Disease Patients with Freezing of Gait: A Randomized Controlled Trial with Plantar Pressure Analysis
Objective: To explore the effect of PD shoes on plantar pressure in PD patients with FOG. Background: Dysfunction of peripheral sensory systems, including decreased cutaneous mechanoreceptors…From the Healthy Brain Ageing – HeBA – Cohort: Motivation for participating in the first online phase of HeBA
Objective: We aim to understand the motivation of participants to join the first online-phase of the European multicenter Healthy Brain Ageing (HeBA; see Abstract 0748_1125_001612)…Low Beta-Band Suppression as a Tool for DBS Contact Selection for Akinetic-rigid Symptoms in Parkinson’s Disease
Objective: To assess the utility of beta-band suppression as a tool for contact selection in patients undergoing nucleus subthalamicus (STN) deep brain stimulation (DBS) for…A randomised, double blind, placebo controlled, crossover trial of incobotulinum toxin A treatment for upper limb tremor
Objective: To assess the clinical and functional outcomes in patients with upper limb tremor with incobotulinum toxin A injections. Background: Upper limb tremor can be…Sex differences in motor and non-motor symptoms in Parkinson’s disease in a diverse East London population
Objective: To investigate sex-related motor and non-motor symptom differences in PD patients in East London. Background: Sex-related differences in motor and non-motor aspects of Parkinson’s…Text entry as a digital outcome in Parkinson’s disease patients (TEXT-PD): results from two exploratory studies
Objective: To evaluate the feasibility and psychometric properties of text entry (TE) and touch metrics as digital outcomes for PD patients. Background: TE on smartphones…
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