Early onset of efficacy during titration in US phase 3 open-label InfusON trial of apomorphine subcutaneous infusion for Parkinson’s disease motor fluctuations
Objective: Evaluate safety/onset of efficacy during titration of continuous subcutaneous apomorphine infusion (CSAI) for motor fluctuations in U.S. outpatients with Parkinson’s disease (PD). Background: Global…COPS: Continuous Observation of Parkinsonian Symptoms – A prospective data acquisition study using wearable accelerometery
Objective: To investigate the continuous and objective assessment of motor symptom severity in Parkinson’s Disease (PD) in everyday life. Background: Treatment adjustments in PD patients…Neurite Orientation Dispersion and Density Imaging and Diffusion Kurtosis Imaging in Brainstem Nuclei for Subtypes of Parkinson’s Disease
Objective: We utilized neurite orientation dispersion and density imaging (NODDI) along with diffusion tensor and kurtosis imaging (DTI/DKI) to assess brainstem nuclei in Parkinson’s disease…Epidemiological analysis of autosomal dominant chorea in Eastern Algeria
Objective: We aim to analyze the main epidemiological characteristics of individuals having a Huntington disease phenotype in Eastern Algeria population. Background: Huntington's disease (HD) is…Validity and Reliability of the Turkish Version of the Radboud Oral Motor Inventory for Parkinson’s Disease (ROMP)
Objective: The aim of this study is to evaluate the validity and reliability of the Turkish version of ROMP for use in clinical settings. Background:…First approach of a sensor-based assessment of the camptocormia angle
Objective: To implement inertial-measurement-unit (IMU) sensors as a reliable and valid diagnostic tool in assessing the camptocormia angle (CA). Background: Camptocormia is a pathological non-fixed…Dopamine-responsive x-linked parkinsonism-epilepsy due to phosphoglycerate kinase-1 deficiency
Objective: To describe the phenotype of three siblings with early-onset parkinsonism and epilepsy due to an x-linked phosphoglycerate kinase 1 deficiency, expanding our understanding of…Longitudinal changes in brain networks associated with clinical symptoms in idiopathic rapid eye movement sleep behavior disorder
Objective: We aimed to assess changes in brain functional networks and accompanying symptoms over years in patients with idiopathic rapid eye movement sleep behavior disorder…Exploring the Effects of Spinal Cord Stimulation for Gait Disturbances in Parkinson’s Disease
Objective: We sought to investigate the effects of SCS in PD, using placebo stimulation, compared to either tonic or burst stimulation paradigms. Background: Gait disturbances…Levodopa-induced orthostatic hypotension in a large cohort of patients with Parkinson’s disease undergoing an acute levodopa challenge test
Objective: We aimed to investigate the frequency and associated risk factors for Levodopa-induced orthostatic hypotension (OH) in a large cohort of PD patients underwent acute…
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