Synaptic density and α-synuclein oligomers in skin biopsies: differences between idiopathic and GBA-linked Parkinson’s disease
Objective: To compare α-synuclein oligomers and synaptic density (SD) in skin biopsies from PD and GBA-PD. Background: Previous research [1] reported α-synuclein oligomers within synaptic terminals of autonomic fibers in…Serotonin Coma: An Antipodal emergency
Objective: To highlight the severity of Serotonin syndrome precipitated in a Psychiatric patient on two unique serotonergic medications leading to a comatose state. Background: Serotonin…STRAT-PARK: a biomarker and stratification initiative for Parkinson’s disease
Objective: The STRAT-PARK initiative aims to stratify Parkinson’s disease (PD) according to underlying molecular mechanisms, and to develop clinically applicable biomarkers for patient stratification. Background:…Clinical characterization of Parkinson’s disease patients with LRRK2 mutation: Insights from a Portuguese reference center
Objective: This study aims to provide a clinical characterization of Parkinson's disease (PD) patients with LRRK2 mutations, who are being treated at a Portuguese reference…The Great Mimicker Strikes Again
Objective: Report the first case of hyperekplexia caused by neurosyphilis. Background: Hyperekplexia is an exaggerated startle reflex appreciated when auditory, tactile, or visual stimuli causes…Characterization of social cognition impairment in Huntington‘s disease
Objective: The aim of the present study is to characterize social cognition deficits in patients of Huntington’s disease (HD) from China and to assess associated factors. Background: Huntington’s…The contribution of Brain Bank for Aging Research to pathomechanism of Parkinson’s disease
Objective: Objective: The aim of this paper is to present the result of the whole body screening of Lewy body pathology by Brain Bank for…Mutation screening of PCDHGB1 variants in a large dystonia cohort
Objective: We aimed to systematically evaluate the genetic associations of PCDHGB1with dystonia in a large Chinese dystonia cohort. Background: Recently, PCDHGB1has been identified to be a novel causative…Reticulospinal tract integrity in patients with SCA12 having impairment of Corticospinal tract- a clinical and electrophysiological study
Objective: Estimate the Reticulospinal tract (RST) activity using StartReact paradigm in patients of SCA12 with clinical and electrophysiological evidence of compromised corticospinal tract (CST) integrity. Background: Spinocerebellar…Blood Pressure Monitoring in Multiple System Atrophy: Focused on Nocturnal Dipping Pattern
Objective: To depict 24 hour blood pressure profile, especially dipping patterns, in subjects with probable and clinically established multiple system atrophy (MSA). Background: Impairment of…
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