Caffeine Intake Interacts with Gene Variants in Parkinson’s disease
Objective: We investigate interactions of caffeine intake with PD risk variants and determine PD risk estimates in caffeine-drinkers carrying these variants. Background: Caffeine intake reduces…Altered nucleus accumbens functional connectivity precedes apathy in Parkinson’s disease
Objective: To investigate whether changes in connectivity between neural regions that are associated with goal-directed behaviour predict future development of apathy in people with Parkinson’s…Towards smart glasses for improved care of individuals with Parkinson’s disease
Objective: To evaluate the applicability of sensor-enabled smart glasses for remote tracking of symptoms related to Parkinson’s disease Background: Diagnosis and monitoring of PD by…Trial protocol: Randomized double blind controlled study to investigate disease modifying effect, safety and optimal dose of oral semaglutide tablet for patients with Parkinson’s disease (MOST-ABLE study)
Objective: This study aims to assess efficacy and disease modifying effect, safety, and optimal dose of oral semaglutide tablet, glucagon-like peptide-1 receptor agonists (GLP-1RAs), for…Metabolic modulation of mitochondrial DNA release in cellular models of Parkin-associated Parkinson’s disease
Objective: Our objective in this study was to elucidate the mechanisms underlying the release of mtDNA in cellular models of Parkin-associated Parkinson’s disease and to…Explainable deep learning based detection of Parkinson’s changes in MRI brain scans
Objective: A pilot study using an AI-based framework to classify routine brain scans as Parkinson’s disease (PD) or control. Background: Prospective neuroprotective treatments for PD…Brain FDG-PET-MRI for early diagnosis of corticobasal syndrome
Objective: To characterize brain fluorodeoxyglucose (FDG) PET-MRI findings in patients with corticobasal syndrome (CBS) and evaluate its utility in early diagnosis of Corticobasal Degeneration (CBD)…Predictive model for Identification of device-aided therapy (DAT) Candidates in Parkinson´s Disease (DELIST-PD Study)
Objective: To develop a classification algorithm based on machine learning to identify candidates for device-aided therapy among patients with Parkinson's disease (PD). Background: DATs (deep…Correlation between fatigue, sleep dysfunction and health-related quality of life in Parkinson’s disease patients
Objective: To determine the correlation between fatigue, sleep dysfunction and health-related quality of life in Parkinson’s disease (PD) patients. Background: Fatigue and sleep dysfunction are…Obesity is a protective factor for the development of Parkinson’s disease in participants of the Framingham Heart Study Cohort
Objective: To determine the role of obesity in the development of Parkinson's disease in a retrospective matched cohort study. Background: Parkinson’s disease (PD) is a…
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