18f-PI-2620 tau PET neuroimaging, tau protein burden and 18f-PI-2620 tau autoradiography on human postmortem brain tissue in a PSP patient
Objective: Our aim is to describe the findings of 18F-PI-2620 tau-PET imaging, together with tau protein burden and 18F-PI-2620 tau autoradiography in brain tissue from…Continuous algorithmic insights into PD motor symptoms and individual treatment response
Objective: To quantify the short-duration levodopa response using high resolution data derived from a wrist sensor and processed with advanced deep learning methods Background: The…Serum neurofilament light-chain concentrations in essential tremor: A case-control study
Objective: We sought to investigate the concentrations of serum neurofilament light-chain (NfL) in essential tremor (ET) patients and healthy controls. Background: Essential tremor is a…Sex Is Not a Major Determinant of Pallidus Internus Deep Brain Stimulation Outcome in Dystonia
Objective: To investigate the role of sex as a biological variable in efficacy and safety of GPi DBS in adults with dystonia. Background: Sex- related…Long-term follow up of Deep Brain Stimulation in Pantothenate Kinase-Associated Neurodegeneration Syndrome: two case reports
Objective: To present the long-term outcomes of deep brain stimulation in two cases of Pantothenate kinase-associated neurodegeneration (PKAN) syndrome. Background: PKAN syndrome is an autosomal-recessive…Left hemisphere theta coherence between cortex and STN increases during speech
Objective: This study contrasts coherence between motor cortex and subthalamic nucleus (STN) field potentials across deep brain stimulation (DBS) implant hemispheres in patients with Parkinson’s…Is an integrated Parkinson’s Dementia Service the way forward?
Objective: To illustrate the role of a single team in managing all facets of Parkinson’s Background: The Cardiff and Vale Parkinson’s service is an integrated,…Next-generation sequencing analysis of circulating microRNAs in multiple system atrophy
Objective: The discriminatory peripheral circulating small non-coding RNAs (sncRNAs) using next-generation sequencing (NGS) between patients of multiple system atrophy (MSA), Parkinson's disease (PD), and healthy controls…Post-Covid parkinsonism: a systematic review of clinical presentations
Objective: We performed a critical appraisal of the COVID-19-related parkinsonism cases reported in the literature so far, providing a phenomenological and diagnostic framework based on…The pivotal difference in gut microbiota between multiple system atrophy and Parkinson’s disease
Objective: The knowledge gap between microbiome dysbiosis and pathogenesis of multiple system atrophy (MSA) remains. Background: Mounting evidence has found significant alterations in the gut…
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