Is cognitive function related to daily life gait and turning in people with Parkinson’s disease?
Objective: We investigated whether cognition and daily-life mobility are associated in people with mild-to-moderate Parkinson's disease (PD). Background: PD is responsible for more mobility disability…An in-vivo study of the integrity of the nigrostriatal pathways in drug-naive Parkinson’s disease patients using [11C]PE2I PET and neuromelanin-Magnetic Resonance Imaging
Objective: This study evaluated the relationship between the neurodegeneration of the substantia nigra neurons, assessed using Neuromelanin-sensitive MRI, and of the loss of striatal dopaminergic…Characterizing Hospital Admissions in Parkinson’s Disease: 10-Year Retrospective Study of Administrative Data in Alberta, Canada
Objective: Characterizing province-wide hospital admissions in persons with Parkinson’s disease (PD) to inform future healthcare improvement in this population. Background: Persons with PD have longer…Bridging the Gap between Statistical significance and Clinical Relevance: A Systematic Review of Minimum clinically important difference (MCID) thresholds of scales reported in trials of Movement Disorders
Objective: To provide a comprehensive review of various patient-reported outcome (PROs) used in movement disorders (MD) research and their MCID values reported in literature. Background:…Real-life heart rate assessment: a digital biomarker for autonomic dysfunction in early Parkinson’s disease?
Objective: To assess whether 1) tremor and dyskinesia affect photoplethysmography (PPG) data quality, and 2) heart rate (HR) analysis based on continuous PPG can be…Observations on 5 Parkinson’s patients taking Mucuna pruriens as natural source of levodopa
Objective: To explore potential benefits and tolerability of extracts from Mucuna pruriens for dopaminergic treatment of Parkinson’s patients. Background: Capsules containing freeze-dried, aqueous extract from…Psychometric properties of the Neuropsychiatric Fluctuations Scale: preliminary results in patients with Parkinson’s disease
Objective: To assess the psychometric properties of the Neuropsychiatric Fluctuations Scale (NFS) [1] in patients with Parkinson’s disease (PD) Background: PD presents with non-motor symptoms…turning alterations detected by mobile health technology in idiopathic rem sleep behavioral disorders
Objective: Aim of the study was to evaluate subtle alterations of turning in iRBD subjects in absence of parkinsonism using Mobile health technology (MHT). Background:…Delayed Diagnosis of Hyperthyroidism in Parkinson’s Disease Patient: A Case Report
Objective: To emphasize the importance of thyroid dysfunction as one of the factors that could exacerbate Parkinson's disease (PD) symptoms. Background: Common endocrine disorder associated…18f-PI-2620 tau PET neuroimaging, tau protein burden and 18f-PI-2620 tau autoradiography on human postmortem brain tissue in a PSP patient
Objective: Our aim is to describe the findings of 18F-PI-2620 tau-PET imaging, together with tau protein burden and 18F-PI-2620 tau autoradiography in brain tissue from…
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