FRMD5 de novo variants in two cases with childhood onset ataxia and seizures
Objective: To describe two cases affected by childhood onset ataxia and seizures carrying de novo variants in the gene FRMD5 Background: FRMD5 belongs to the…Defining neuropsychiatric symptoms fluctuations in Parkinson’s disease
Objective: To evaluate the demographic and clinical correlates of Parkinson’s disease (PD) patients with fluctuations of neuropsychiatric symptoms (NPS-F). Background: Clinical correlates of fluctuations of…Moving beyond trial and error: a strategy for anatomically informed contact selection in subthalamic deep brain stimulation for Parkinson’s disease.
Objective: In this study we aimed to investigate and compare the utility of conventional DBS programming strategies and anatomically informed approaches predicting long term motor…Utilization pattern and factors associated with amantadine use in Parkinson’s disease (PD) of the French NS-Park cohort
Objective: To assess amantadine use in the French NS-Park cohort and factors associated with its prescription Background: Amantadine, a unique dopamine/glutamate drug, is approved worldwide…Effects and neural mechanisms of training involving rhythmic auditory stimulation on upper-limb movements in patients with Parkinson’s disease
Objective: This study is to examine effects and neural mechanisms of training involving rhythmic auditory stimulation on upper-limb movements in patients with Parkinson’s disease (PD).…Asymptomatic Gaucher disease presented as Parkinsonism in 61 years old patient.
Objective: Gaucher disease is an inherited disease caused by a mutation in the glucocerebrosidase gene, causing visceral, hematologic, and skeletal involvement. [1] [2] We report…Dysconnectivity Profiles of Raphe Nuclei in Parkinson’s Disease: From Prodromal to Advanced Stage
Objective: To investigate the functional connectivity changes of dorsal raphe (DR) and median raphe (MR) nucleus in patients with PD from the prodromal to advanced…Psilocybin therapy for depression and anxiety associated with Parkinson’s disease: a pilot study (NCT04932434)
Objective: To investigate the safety, tolerability, feasibility, and preliminary efficacy of moderate and high dose psilocybin treatment with psychotherapeutic support for comorbid Parkinson's disease (PD)…Effects of physical exercise interventions on cognitive function in Parkinson’s disease: an updated systematic review and meta-analysis of randomized controlled trials
Objective: To determine whether physical exercise interventions can improve cognitive function, including overall performance and specific domains, in patients with Parkinson’s disease (PD) and to…The natural history of Parkinson’s disease in LRRK2 G2019S carriers
Objective: To document differences between the evolution of self-reported symptoms and prodromal markers in LRRK2 G2019S carriers and non-carriers with and without Parkinson’s Disease (PD).…
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