Clinical-based diagnosis and self-reported Parkinson’s disease in a population-based sample in southern Brazil
Objective: To report the frequency of self-reported PD and the diagnostic evaluation performed by clinical neurologists in a population-based cohort from south Brazil. Background: It…Challenges with oral anti-parkinsonian medications and opportunities with continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa (LDP/CDP) for treatment of advanced Parkinson’s Disease (aPD)
Objective: To understand people with Parkinson’s (PwP) experience with their advancing disease and identify factors for PwP to initiate and continue on LDP/CDP as treatment…The Roche ‘End-to-End Matrix’ for Patient-Centric Drug Discovery and Development – Focus on Parkinson’s disease
Objective: To develop an ‘End-to-End Matrix’ for Patient-Centric Drug Discovery and Development to increase the probability of success of clinical trials in Parkinson’s disease. Background:…Effects of a rhythmic auditory stimulation-enhanced walking program on Veterans with Parkinson’s disease with and without subthalamic nucleus deep brain stimulation.
Objective: Describe outcomes from a 12-week home-based rhythmic auditory stimulation (RAS)-enhanced walking program completed by Veterans with Parkinson’s disease (PD); 1 with subthalamic nucleus deep brain stimulation…The PD-Ballet study: a randomised controlled, single-blinded trial of dance therapy for Parkinson’s, baseline characteristics of the study cohort
Objective: To describe baseline characteristics of the cohort of participants recruited to a world-first randomised controlled single blind trial of ballet-based dance intervention for holistic…Modulation of autophagy and neuroinflammation by Niclosamide in MPTP Induced- Parkinson’s disease model
Objective: The current investigation aimed to investigate the neuroprotective effect of niclosamide (NI) on autophagy and neuroinflammatory pathways in Parkinson’s disease (PD). Background: Autophagy dysregulation…Use of insect model to study Parkinson’s disease pathophysiology by inducing GSH-depletion and behavioral deficits among larvae: Evidences of ameliorative properties of phytoconstituents
Objective: The purpose of the study is to establish an all-around model for Parkinson's disease using Drosophila melanogaster, the fruit-fly in order to understand behavioral…Posturography as an objective measure of disease progression and prognostication in Progressive Supranuclear Palsy
Objective: To determine the usefulness of posturography as an objective measure of disease progression and prognostication on Progressive Supranuclear Palsy (PSP). Background: To date, interventional…The prevalence and clinical features of GBA-related Parkinson’s disease in a Slovak patient cohort
Objective: The aim of our study was to determine the prevalence and clinical characteristics of Slovak GBA-related patients with Parkinson's disease (PwP). Background: GBA variants…Drug-induced Parkinsonism and nonmotor symptoms: a case of gustatory rhinorrhea
Objective: We aim to emphasize the relevance of contemplating nonmotor symptoms as possible features of drug-induced parkinsonism, and the utmost importance of further investigation in…
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