Voice- tremor in a patient with positive VPS 16 nonsense mutation: Expanding the phenotype
Objective: Reporting a case of voice-tremor in a patient with heterozygous non-sense variation in exon 16 of VPS 16 gene Background: Dystonia-30 is caused by…Data-driven subtypes of multiple system atrophy and the implication on prognosis
Objective: To determine the clinical subtypes of MSA using data-driven approach and to compare the differences of the subtypes on survival and bed-ridden rates. Background:…Focused ultrasound as rescue treatment of essential tremor after deep brain stimulation.
Objective: To describe a case of disabling essential tremor (ET) treated with unilateral MRI-Guided Focused Ultrasound (FUS) thalamotomy as rescue treatment after deep brain stimulation…Sensor-based digital measurement of gait and wrist pronation-supination in clinically-defined classes of Parkinson’s disease progression identified by unsupervised clustering
Objective: To determine how sensor-based measurement of motor performances relate to the heterogeneity of clinical progression in early Parkinson’s disease (PD). Background: Observed disease progression…A 16-week open-label study of the effects of treatment with pimavanserin on activities of daily living in subjects with Parkinson’s disease psychosis (PDP)
Objective: To examine the effects of pimavanserin on activities of daily living during treatment for Parkinson’s Disease psychosis. Background: Accurate assessment of disability associated with…Dopaminergic neuronal cell therapy for Parkinson’s Disease: results from a phase 1 study of Bemdaneprocel
Objective: This first-in-human Phase 1 study aims to assess the safety, tolerability, clinical efficacy, and functional imaging measures of bemdaneprocel in subjects with PD. Background:…Predicting clinical response after Gamma Knife thalamotomy in essential tremor
Objective: To determine clinical, surgical and radiological factors associated with tremor reduction after Gamma Knife thalamotomy (GKT) for essential tremor (ET). Background: GKT is a…Deep brain stimulation for the management of movement disorders in Rett syndrome
Objective: We present two patients with Rett syndrome who underwent deep brain stimulation (DBS) for management of action tremor and rigidity. Video segments of the…Brain-behavior quantification and synchronization to drive closed-loop deep brain stimulation
Objective: Closed-loop DBS systems require a neural biomarker to responsively turn on stimulation, which in turn requires neurophysiological quantification synchronized to behavior or symptoms. Our…Determinants of care partner burden in atypical parkinsonian syndromes
Objective: To understand the determinants of burden among people caring for individuals diagnosed with progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), or multiple system atrophy…
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