In vivo assessment of striatal compartments in patients with idiopathic upper limb dystonia
Objective: To access striatal matrix and striosome compartments in patients with idiopathic upper limb dystonia using diffusion tensor imaging Background: The striatum is an essential…Deep brain stimulation for the management of movement disorders in Rett syndrome
Objective: We present two patients with Rett syndrome who underwent deep brain stimulation (DBS) for management of action tremor and rigidity. Video segments of the…Brain-behavior quantification and synchronization to drive closed-loop deep brain stimulation
Objective: Closed-loop DBS systems require a neural biomarker to responsively turn on stimulation, which in turn requires neurophysiological quantification synchronized to behavior or symptoms. Our…Determinants of care partner burden in atypical parkinsonian syndromes
Objective: To understand the determinants of burden among people caring for individuals diagnosed with progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), or multiple system atrophy…Sleep hygiene practice in patients with Parkinson’s disease
Objective: We examined the prevalence of diverse sleep hygiene behavior and their associations with insomnia severity in PD patients.We examined the prevalence of diverse sleep…Radiological markers of CSF α-synuclein aggregation in Parkinson’s disease patients
Objective: To investigate the association between cerebrospinal (CSF) αS aggregates, MRI, and dopamine transporter spectral tomography (DaTscanTM) imaging metrics. Background: Synuclein amplification assays (SAA) enables…Effect of intensive Game-based neurorehabilitation (GBNR) on gait, balance and quality of life (QOL) in Parkinson’s patients: A prospective randomized control study
Objective: To assess changes in the gait, balance and QOL in PD patients subjected to intensive GBNR in comparison with conventional Neurorehabilitation (NR) therapy using…Concealment of Parkinson’s Disease: Prevalence and Impact on Health and Quality of Life
Objective: (1) To explore the proportion and personal characteristics of patients who do not disclose their diagnosis of Parkinson's disease (PD) to their family, and…Underutilization of Neurology and Rehabilitation Services among People with Parkinson’s Disease
Objective: to map utilization of neurology and rehabilitation services by people with Parkinson’s disease (PD), and to identify associations between utilization and demographics. Background: People…The impact of wearing ‘OFF’ (WO) episodes on non-motor symptoms (NMS) burden and quality of life (QoL) in Parkinson’s disease (PD) patients
Objective: To estimate the frequency and severity of NMS and their impact on QoL among patients with moderate to advanced PD with WO episodes versus…
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