A phase 2 randomized, double-blind, placebo-controlled trial of Ambroxol as a disease-modifying treatment for Parkinson’s disease dementia.
Objective: To evaluate the safety and tolerability of repurposing Ambroxol as a disease modifying treatment for Parkinson’s Disease Dementia (PDD). Background: Carrying a mutation in…Does fatigue in Parkinson’s disease impact one’s physical function in daily live?
Objective: To investigate fatigue at baseline and 3.5 years later and its association with balance and gait over time. Background: In Parkinson’s disease (PD), fatigue…Substantia Nigra blood-brain barrier opening in Parkinson´s disease: PET (18F-Choline) evidence of parenchymal penetration
Objective: To evaluate clinical safety, feasibility, and tissue penetration (by 18F-Choline PET) of MR-guided focused ultrasound (MRgFUS) blood-brain barrier opening (BBB-O) of the substantia nigra…Tourette Syndrome with Functional Overlay: A Diagnosis Challenge and The Role of Electrophysiological Study
Objective: To highlight the role of electrophysiological study (Ephy) as a useful diagnostic tool. Background: Tics with functional overlay are characterised by acute worsening of…Does sleep disorder affect cognitive impairment in Parkinson’s disease?
Objective: The aim of this study was clarified the relationship between cognitive dysfunction and sleep disorders in Parkinson's disease(PD). Background: In PD, cognitive decline increases…Technological visuo-cognitive training in Parkinson’s disease: Preliminary findings from a pilot randomised controlled trial
Objective: To determine the feasibility and preliminary efficacy of a home-based, technological visuo-cognitive training (TVT) intervention using a mobile application and exercise with stroboscopic glasses…Investigation of usefulness of new MSA diagnostic criteria
Objective: We investigated the utility of the Movement Disorder Society Criteria (MDS criteria) including sensitivity and specificity. Background: Multiple system atrophy (MSA) is an adult-onset…Learnings from inaugural year of foundation sponsored genetic counseling and testing program for Spinocerebellar Ataxia (SCA) types 1, 2, and 3
Objective: To describe volume, genetic results, and participant perceptions of foundation sponsored genetic counseling and testing program for SCA 1, 2, and 3. Background: Molecular…Probiotics for treatment of constipation in Parkinson’s patients: a systematic review and meta-analysis
Objective: The objective of this systematic review and meta-analysis of published clinical trials is to investigate the probiotics' efficacy in treating constipation in Parkinson’s patients.…Dyskinesia and adherence to safinamide and opicapone in fluctuating patients with Parkinson’s disease: observational retrospective study
Objective: To assess differences in the new onset or worsening of baseline dyskinesia after the introduction of safinamide (SA) or opicapone (OP) as add-on therapy…
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