Genetic and psychiatric risk factors for impulse control disorders in de novo Parkinson’s disease
Objective: To assess the interplay of polygenic dopamine risk scores and psychiatric symptoms in the development of impulse control disorders (ICDs) in de novo patients…Quantitative analysis of speech diadochokinetic rate in hereditary spastic paraplegia SPG3A
Objective: To analyze the dysarthria and speech diadochokinetic rate in a patient with hereditary spastic paraplegia (SPG3A). Background: Hereditary spastic paraplegias (HSP) are about 80…Non-motor symptoms of Parkinson’s disease: an analysis of gender and age-related differences in a large online cohort
Objective: This study analyzed non-motor symptoms in newly diagnosed Parkinson’s disease (PD) patients and controls in a large online cohort, comparing four groups based on…Multicenter, randomized, placebo-controlled, double-blind, parallel-group proof-of-concept study of lixisenatide in patients with early Parkinson’s disease (PD): the LIXIPARK trial (NCT03439943)
Objective: To evaluate the “disease-modifying” effect of lixisenatide as adjunct to antiparkinsonian medications in patients with early PD. Background: Lixisenatide, a glucagon-like peptide 1 receptor…Stability of basal ganglia beta band power distribution during continuous deep brain stimulation in Parkinson’s disease: analysis of sub-cohort from the ADAPT-PD trial
Objective: To assess the stability of the daily distribution of peak subthalamic nucleus (STN) and globus pallidus internus (GPi) beta band power during continuous deep…Evaluation of Cognitive Assessment Tools in Parkinson’s Disease
Objective: To evaluate a variety of cognitive assessment scales in a longitudinal Parkinson’s disease (PD) cohort. Background: Cognitive impairment is one of the most common and…Chronic pain and the polytrauma clinical triad are risk factors for prodromal PD
Objective: This study aimed to assess whether chronic pain is a risk factor for prodromal Parkinson disease and determine if pain severity and comorbidity with…Sensitivity, consistency and test-retest reliability of home-based freezing of gait-provoking tests in people with Parkinson’s disease
Objective: To evaluate the sensitivity, consistency and test-retest reliability of several freezing of gait (FOG)-provoking tests in the homes of people with Parkinson’s disease (PD)…A Case of Post-malaria neurological syndrome presenting with tremor
Objective: We report a case of post-malaria neurological syndrome (PMNS) presenting with tremor in a Korean patient. Background: PMNS is a rare neurological complication which…Effects of GBA1 mutations and STN-DBS on response inhibition in Parkinson’s disease
Objective: To determine specific pattern of cognitive dysfunction in Parkinson’s disease (PD) patients who are glucocerebrosidase mutation carriers (PD-GBA1) compared with non-mutation carriers with and…
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