Analyzing the metabolic function of DJ-1 in the pathogenesis of Parkinson`s disease (PD) and Glioblastoma multiforme (GBM)
Objective: In this project, we are comprehensively studying the function of DJ-1 in PD and GBM to better understand its observed role in both, neurodegeneration…Impact of ApoE genotype on cognition in idiopathic and genetic forms of Parkinson’s disease
Objective: The aim of our current report was to assess the impact of Apolipoprotein-E (ApoE) genotype on cognition in idiopathic Parkinson’s disease (PD) patients and…Subcutaneous Foslevodopa/Foscarbidopa in Patients With Advanced Parkinson’s Disease: Results From a Randomized, Double-blind, Double-dummy Phase 3 Trial
Objective: To evaluate the efficacy and safety/tolerability of 24-hour/day continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa (a soluble formulation of levodopa/carbidopa prodrugs) vs oral levodopa/carbidopa in…Neurofilament light chain protein (NfL) is elevated in Essential Tremor
Objective: To investigate neurofilament light chain protein (sNfL) concentrations in serum in Essential Tremor (ET) compared to healthy controls and to assess whether sNfL is…Expression perception and timing in people with Parkinson’s Disease
Objective: To develop a paradigm to test whether the perception of mouth movements is improved when movements occur at a predictable point in time. In…In Silico Study Reveals Cocaine Exposure Modulates Dopamine Neuron Firing Patterns by Inhibiting Small Conductance Calcium Activated Potassium Current
Objective: The neurological reason behind the loss of dopamine neurons causing Parkinson’s disease (PD) is an unsolved mystery. Background: As PD is identified as a…A CASE OF MEIGE SYNDROME IN INDONESIA TREATED WITH HALOPERIDOL
Objective: To give a brief picture about the challenge of diagnosing and treating patients with Meige syndrome and to report a case of Meige syndrome…Cognitive Function in Late-life and Parkinson’s Disease Neuropathology at Death
Objective: To examine the association between cognitive function in late-life and Parkinson’s disease (PD) neuropathology at death, including 1) neuron loss in the locus coeruleus…Non-motor symptoms burden in motor-fluctuating patients with Parkinson’s disease may be alleviated by safinamide: the VALE-SAFI study
Objective: The present study aimed to explore the effect of safinamide treatment on NMS and quality of life in motor-fluctuating PD patients. Background: Parkinson’s disease…Continuous Dopaminergic Stimulation (CDS), different infusion rates
Objective: Physiopathological and therapeutic discussion of motor complications and dyskinesias in patients treated with continuous dopaminergic stimulation Background: Levodopa -induced motor complications remain an important…
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