Clinical and risk profiles of Parkinson’s disease from a large pan-India cohort: interim observations of the GAP-India study
Objective: To create a pan-Indian clinical repository of Parkinson’s Disease (PD). Background: The genetic risk for PD in India is unknown. The Luxembourg-German India Alliance…Digital Sway Measures for Spinocerebellar Ataxia
Objective: The objective of the study was to investigate which postural sway condition and which measures are most sensitive to prodromal and manifest spinocerebellar ataxia…Social Withdrawal in Parkinson’s Disease: A Scoping Review
Objective: We conducted a scoping review to understand the nature and impacts of social withdrawal in PD and identify evidence gaps. Background: Social withdrawal has…A secretory vesicle failure in Parkinson’s disease occurs in human platelets
Objective: Since platelets use similar, if not the same, mechanisms to accumulate serotonin (5-HT) as dopaminergic neurons to store DA in their VS; we wonder…Probable Four-repeat tauopathy criteria in Corticobasal Syndrome: diagnostic accuracy, clinical features and imaging biomarkers
Objective: To compare the “probable four-repeat (4R)-tauopathy” criteria[1] with the clinical research(cr) criteria for corticobasal degeneration (CBD) [2] regarding diagnostic accuracy to predict a negative…Successful deep brain stimulation for bilateral Holmes tremor caused by progressive multifocal encephalopathy.
Objective: To report a unique case of a patient with acquired Holmes tremor (HT) secondary to Human Immunodeficiency Virus (HIV) and progressive multifocal leukoencephalopathy (PML)…Fatigue at different stages of parkinson’s disease
Objective: study fatigue as a key non-motor symptom of parkinson's disease Background: Fatigue in PD refers to a state of fatigue, lack of energy, a…Clinical and biomarker characteristics of Huntington’s Disease patients recently proposed for huntingtin-lowering clinical trial inclusion
Objective: We investigated plasma NfL levels, as well as clinical measures, in Huntingtin (Htt)-mutation carriers 48 years of age and under, with a CAP score…Pons and middle cerebellar peduncle diameters are diagnostic of Multiple System Atrophy of the Cerebellar Type (MSA-C)
Objective: To develop an MRI biomarker for the definitive diagnosis of Multiple System Atrophy of the Cerebellar Type (MSA-C). Background: MSA is a sporadic, adult-onset…Jumping the Gun Sign: a sign for “Waiting Impulsivity” of progressive supranuclear palsy
Objective: We presumed that the “jumping the gun sign (JGS)” is caused by an impairment of “waiting impulsivity” rather than “stopping impulsivity”, as seen on…
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