A randomized controlled trial comparing the efficacy and safety of pyridostigmine versus midodrine for the treatment of orthostatic hypotension in Parkinson’s disease patients
Objective: To assess the long-term efficacy and safety of pyridostigmine and midodrine in the treatment of OH in PD. Background: In Parkinson's disease (PD), orthostatic…Movement disorders with phosphodiesterase 10A IgG autoimmunity
Objective: To report four new cases of phosphodiesterase 10A (PDE10A) IgG neurological autoimmunity. Background: PDE10A IgG was recently identified as a biomarker of paraneoplastic neurological…Cognitive performance and learning parameters predict response to working memory training in Parkinson’s disease
Objective: The present study aims to evaluate a multivariable model to predict verbal working memory (WM) performance following a targeted cognitive training intervention, WM training…X-Linked Dystonia Parkinsonism as the cause of Isolated Lingual Dystonia (ILD)
Objective: This report aims to describe a 43-year-old Filipino male with ILD aggravated by speech and swallowing. This paper highlights the importance of including XDP…Short report in a dystonia cohort patients with implanted DBS systems
Objective: To review the use of bipolar and monopolar stimulation in a cohort of patients implanted DBS with Generalized Dystonia between 2012-2021 in Federal Center…An automated data cleaning approach to remove preparation artefacts from brain histology slide images
Objective: To present the potential application of an automated image analysis pipeline called WSIQC for the cleaning and quality assessment of brain histology images. Background:…An automated AI-based framework for putamen volume measurement in MSA
Objective: The putamen is a difficult structure to segment accurately, and automated methods require manual editing to improve segmentation accuracy. Our aim was to test…De novo mutation in TMEM151A and Paroxysmal Kinesigenic Dyskinesia
Objective: To confirm the association between TMEM151A mutation and paroxysmal kinesigenic dyskinesia. Background: Heterozygous mutations in TMEM151A, encoding a protein of undetermined function, have been…Classification of extremity movements by visual observation of signal transforms
Objective: To create a tool for raters certified in the MDS-UPDRS) [1] to blindly score online signal transforms of the output of the wearable sensors to…Newly identified cases of parkinsonism and prodromal PD in a remote LRRK2 G2019S cohort
Objective: To evaluate new cases of prodromal PD and concern for parkinsonism in a cohort of LRRK2 G2019S carriers. Background: LRRK2 G2019S is a common…
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