Overnight stimulation: a new rescue strategy for deep brain stimulation-induced bradykinesia in dystonia?
Objective: We report the serendipity case of overnight stimulation for the management of stimulation-induced bradykinesia in two patients with generalized dystonia and clinically-effective pallidal deep…Levodopa–entacapone–carbidopa intestinal gel infusion for advanced Parkinson’s disease patients – data from a Romanian center
Objective: To report the experience with levodopa–entacapone–carbidopa intestinal gel infusion (LECIG) for the management of advanced Parkinson’s disease (PD) from a Romanian center. Background: LECIG…The role of cortical and subcortical structures in maintaining efficient network topology in Parkinson’s disease
Objective: To assess the relative importance of cortical and subcortical nodes and their connections in maintaining efficient structural connectome topology in Parkinson's disease (PD). Background:…Giant symptomatic capillary telangiectasia: uncommon cause of cerebellar ataxia
Objective: We present a case of a patient with adult-onset cerebellar ataxia and palatal tremor secondary to an uncommon vascular cause. Background: Capillary telangiectasias (CT)…Dried blood and plasma spots for the measurement of neurofilament light chain and inflammatory cytokines in patients with REM sleep behaviour disorder
Objective: The objective of this study was to investigate the relationship between plasma and dried blood/ plasma spot measurements of inflammatory markers (IFN-ɣ, IL-1β, IL-6,…Physician satisfaction from continuous telemonitoring in Parkinson’s disease
Objective: This work presents an evaluation of the satisfaction of physicians from using a continuous telemonitoring system for patients with Parkinson’s disease (PD). Background: The…Pilot study to investigate the use of in-clinic sensing to identify optimal stimulation parameters for deep brain stimulation therapy in Parkinson’s disease
Objective: Compare the use of in-clinic sensing functionality and standard of care monopolar review for identifying optimal settings of a deep brain stimulation (DBS) in…Parkinson`s disease in Pandemic Covid
Objective: SARS-CoV2 infection invades the brain through ACE2 receptors or the cytotoxic aggregation of proteins, including α-synuclein.Studies are uncertain on the risk of COVID and…Parkin deficiency impairs mtDNA dynamics and propagates inflammation
Objective: We sought to explore Parkin’s role in (i) averting neuronal mtDNA dyshomeostasis/release and (ii) the activation of downstream inflammatory processes. Background: Mutations in Parkin…Initial Postmarketing Real World Experience with directSTIM™ DBS System: A Case Series
Objective: In this study we report the first three cases of a new, CE-marked system for deep brain stimulation. Background: The PMCF study is a…
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