Longitudinal clinical and biomarkers characteristics of non-manifest LRRK2 G2019S carriers: The PPMI cohort
Objective: To examine 2-year longitudinal change in clinical, dopamine transporter (DAT) imaging and biofluid biomarkers in non-manifesting carriers (NMCs) of LRRK2 G2019S versus healthy controls…Longitudinal study of Parkinson’s disease-related pattern with resting state functional MRI
Objective: To validate the previously characterized resting-state fMRI (rs-fMRI) Parkinson’s disease (PD)-related pattern, termed fPDRP, in a large multi-site PD imaging database, and to assess…P2B001 in the management of untreated PD. Results from a randomized, double-blind, double-dummy controlled trial
Objective: Evaluate the efficacy and safety of P2B001 compared with its components and with Extended-Release pramipexole (ER-PPX, calibration arm) in untreated PD. Background: P2B001 is…Postural Instability in Parkinson’s Disease: Phenotypic data from The Cincinnati Cohort Biomarker Program
Objective: To estimate the onset of postural instability in a cohort of Parkinson's disease (PD) patients. Background: The Cincinnati Cohort Biomarker Program (CCBP), launched in…Caregiving patients with Parkinson disease treated with deep brain stimulation: a systematic review and meta-synthesis of qualitative research
Objective: To explore the experiences and unmet needs of Parkinson disease patients (PDPs) caregivers after subthalamic nucleus deep brain stimulation (STN-DBS) by performing a systematic…Nutritional Status of Patients with Parkinson’s Disease: Report from Indonesian Tertiary Referral Hospital
Objective: This study aimed to describe and determine the prevalence of nutritional status in outpatient Parkinson’s Disease (PD) patients. Background: Parkinson’s disease is the most…Non-Invasive Brain Stimulation for the Treatment of Psychiatric Symptoms in Parkinson’s Disease: A Systematic Review and Meta-analysis
Objective: This meta-analysis aims to assess the effect of NIBS technique for psychiatric symptoms in patients with PD. Background: Non-invasive brain stimulations (NIBS), especially repetitive…Imaging progressive peripheral and central dysfunction in isolated REM sleep behaviour disorder after 3 years of follow-up
Objective: To image progression of intestinal dysfunction, cardiac sympathetic denervation, and dopaminergic nigrostriatal damage in patients with isolated REM sleep behaviour disorder (iRBD). Background: A…Substantia nigra dopaminergic neuron density in PD, PSP and MSA: An interim clinicopathological analysis
Objective: To investigate substantia nigra pars compacta (SNc) area together with dopaminergic neuron count and density in atypical parkinsonisms in relation to Parkinson’s disease (PD)…Subgroup analyses by Unified Parkinson’s Disease Rating Scale Part III (UPDRS-III) of patients treated with levodopa inhalation powder 84mg or placebo to treat OFF symptoms in patients with Parkinson’s disease (PD)
Objective: An analysis of the proportion of patients who turned ON after levodopa inhalation powder (CVT-301) 84mg treatment vs placebo, compared across subgroups of patients…
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