Challenging diagnosis of familial Gerstmann-Straussler-Scheinker disease with normal brain image: a case report and systematic review
Objective: We report a case of familial Gerstmann-Straussler-Scheinker (GSS) disease, who presented with cerebellar ataxia, but did not show abnormalities in diffusion weighted image (DWI)…Protective effects of Hibiscus sabdariffa extracts in 6-hydroxydopamine-lesioned parkinsonism.
Objective: The therapeutic effects of Hibiscus sabdariffa (HS) were investigated in parkinsonism rats induced by 6-hydroxydopamine (6-OHDA). Background: The oxidative stress is an important component…Association of glucocerebrosidase genotype and disease progression in early Parkinson’s disease over the course of 80 weeks
Objective: *Background and objectiveWe conducted post-hoc analyses with data of the Levodopa in EArly Parkinson’s disease (LEAP) study to compare the rate ofdisease progression in…Beta-agonists and risk of Parkinson’s disease: Meta-analysis of real-world evidence studies
Objective: We performed a systematic review and meta-analysis of real-world evidence (RWE) studies evaluating the association between use of beta-agonist and the risk of PD.…Safety of opicapone after 5 years of post-marketing experience worldwide
Objective: To review the safety data of opicapone (OPC) after five years of marketing experience worldwide Background: OPC is a once-daily catechol-O-methyltransferase (COMT) inhibitor proven…OCEAN Study in Parkinson’s Disease: Status Update of a Randomised Double-Blind Placebo-Controlled Trial of Opicapone
Objective: This study aims to evaluate if treatment with opicapone (OPC) 50 mg once-daily can improve motor fluctuation (MF)-related pain in patients with Parkinson’s disease…Variability in Age of Onset, Age of Diagnosis and Age of Death for Progressive Supranuclear Palsy Patients Among Three Racial Groups in Hawai`i
Objective: To examine if differences in age of symptom onset, age of diagnosis, age of death, and number of years lived after diagnosis exist for…Perception-action binding in patients with functional movement disorders
Objective: To analyze cognitive processes engaged in linking and restructuring sensory perception and motor action associations in functional movement disorders (FMD). Background: FMD patients demonstrate…Patients with Parkinson’s Disease Share a Unique Olfactory Perceptual Fingerprint
Objective: To explore potential olfactory biomarkers for early detection of Parkinson's disease Background: Although the olfactory decline in Parkinson’s disease (PD) precedes the motor symptoms…‘Top of the POPPS’ – how we set up an online support group for Partners of People with Parkinson’s.
Objective: To provide useful peer and professional support for partners of people with Parkinson's (PWP)To be able to offer that support in a Covid safe…
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