A One-year follow-up study of effects of voltage/frequency Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) adjustments on speech intelligibility in Parkinson’s Disease (PD)
Objective: To assess the relationship between along-1-year stimulation voltage(V)/frequency(F) adjustments and speech intelligibility (SI) in PD patients treated with STN-DBS. Background: Low V/F stimulation improves…Continuous circadian intracerebroventricular administration of anaerobically preserved dopamine greatly reduces severe L-dopa-related complications in Parkinson’s disease
Objective: We aim to demonstrate the safety and efficacy of continuous circadian intracerebroventricular (i.c.v.) administration of anaerobic-dopamine (A-dopamine) to reduce the L-dopa-related complications (LDRC) in…Association of accelerometer-derived sleep and idiopathic dystonia: A UK Biobank cohort study
Objective: To assess the rate and nature of sleep disturbances in dystonia, and to examine the extent to which disturbance to sleep is associated with…The overexpression of a-SYN leads to a differential process of mitophagy in neurons and atrocytes
Objective: To determine the role of the different mitophagy pathways involved in PD, a key question that is still unresolved. We will investigate whether a-synuclein…Gray matter volume of proposed brain-first and body-first Parkinson’s disease subtypes
Objective: The aim of this study was to test if markers of the brain-first Parkinson’s disease (PD) subtype are associated with a greater or more…ER Visits and Hospitalizations Among Patients Treated with Pimavanserin or Other-AAPs for Parkinson’s Disease Psychosis: Analysis of Medicare beneficiaries
Objective: To examine health resource utilization (HRU) outcomes among PDP patients treated with PIMA vs. other AAPs. Background: Real-world analysis demonstrating pimavanserin (PIMA) benefits, the…The association of CSF sTREM2 with cognitive decline and its dynamic change in Parkinson’s disease: Analysis of the PPMI Cohort
Objective: This study aims to investigate the baseline and longitudinal changes of soluble fragments of triggering receptor expressed on myeloid cells 2 (sTREM2) in cerebrospinal…Combining intraoperative microelectrode recordings with postoperative transcranial B-mode sonography of the brainstem to estimate the anatomical position of the electrode for chronic subthalamic nucleus deep brain stimulation in Parkinson´s disease
Objective: We tested whether the position of the electrode for deep brain stimulation (DBS) could be assessed relative to subthalamic nucleus (STN) dorsal boundaries by…Referral for movement disorder specialists within a central hospital
Objective: Characterization of in-hospital observation requests for movement disorders specialty. Background: The increasing prevalence of movement disorders may lead to high patient referral for movement…Evaluation of an Oral Health Questionnaire in Parkinson’s Disease to Facilitate a Multi-disciplinary Approach to improving Care Through Education
Objective: To determine if the oral health questionnaire (OHQ) devised could help to promote good oral hygiene in Parkinson’s disease (PD) while considering the potential…
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