Sex Differences for Tau Association with Cognition in Early Parkinson’s Disease
Objective: To assess sex differences for cerebrospinal fluid (CSF) phosphorylated tau (p-tau) association with cognition in Parkinson’s disease (PD) Background: Tau biomarkers can predict cognitive…Lewy body disease clinical subgroups present similar disease progression rates
Objective: To characterize LBD clinical subgroups and identify possible differences in disease progression. Background: Patients with Lewy body disease (LBD) present a wide variety of…LIG1 polymorphism modifies the age at onset in patients with Spinocerebellar Ataxia type 2
Objective: Assessing the role of LIG1 Exon 6 A→C polymorphism acting as a modifier of clinical severity in patients with Spinocerebellar ataxia type 2 (SCA2).…Time-to-event approach mitigates the treatment masking effect of symptomatics on MDS-UPDRS Part III
Objective: To assess whether a time-to-event (TTE) approach may mitigate the masking effect of changing symptomatic therapy on Movement Disorders Society–Unified Parkinson’s Disease (PD) Rating…Local Field Potential Recordings in Parkinson’s Disease at Home: A Case Series Report
Objective: To report novel, real-world use of chronic local field potential (LFP) sensing in patients with Parkinson’s disease (PD) outside-of-clinic settings. Background: Recent advancements in…ADS024 attenuates striatal dopamine loss and restores movement in animal models of Parkinson’s disease
Objective: To evaluate the effect of ADS024, an oral single strain live biotherapeutic product (SS-LBP), on the pathophysiology of MPTP-induced Parkinson’s Disease (PD) phenotypes in…Improvement of movement disorder and neurodevelopment under selegiline in a CLTC deficient patient
Objective: We report the significative improvement on both movement disorder and neurodevelopment in a 5-year-old CLTC deficient patient treated with selegiline. Background: In 2019 we described a 30-year-old woman…DaxibotulinumtoxinA for Injection in Adults With Upper Limb Spasticity After Stroke or Traumatic Brain Injury: A Randomized Placebo-Controlled Study (JUNIPER)
Objective: To evaluate the efficacy and safety of 3 doses of DaxibotulinumtoxinA for Injection (DAXI) vs placebo for adults with upper limb spasticity (ULS) after…Dual target deep brain stimulation for clinically complex tremor disorders: a single centre prospective study
Objective: We present a case series of patients with refractory complex tremor treated with dual targeting DBS of ViM and pSTN/cZI. Background: The ventral intermediate (ViM) nucleus…Survival and progression in GBA-associated dementia with Lewy bodies
Objective: To assess the impact of GBA mutations and APOE polymorphisms on progression and survival in a cohort of Ashkenazi Jewish (AJ) patients with DLB.…
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