Depression and progression of motor symptoms in early stage of Parkinson’s disease
Objective: To investigate the association of depression with the progression of motor symptoms in patients with early-stage PD. Background: Depression is a major nonmotor symptom…Psychometric characteristics of the Neuropsychiatric Fluctuation Scale
Objective: To evaluate the psychometric properties of the Neuropsychiatric fluctuation scale (NFS) for Parkinson’s disease (PD). Background: Neuropsychiatric fluctuations (NpsyF) in PD are frequent and…Visual system abnormalities and visual hallucinations in Parkinson’s disease
Objective: We aimed to identify clinical and imaging biomarkers of visual system injury associated with the presence of Visual hallucinations (VH) in Parkinson's disease (PD).…Priorities of PD patients for treatment of cognitive-driven ADL impairment
Objective: To define cognitive-driven impairments in activities of daily living (ADL) with high priority for rehabilitation ranked by Parkinson’s disease (PD) patients. Background: Impairments in…Blood-derived α-synuclein from Parkinson´s disease patients is able to seed pathology
Objective: To identify seeding capacities of soluble α-synuclein (α-syn) conformers derived from neuronal extracellular vesicles (NEs) from Parkinson´s disease (PD) patients. Background: PD pathology is…Developing New Insights Into Clinical and Genetic Features of PD – The Global Parkinson’s Genetics Program (GP2) Clinical Cohorts Working Group
Objective: We aim to recruit Parkinson’s cohorts across the world for the Global Parkinson’s Genetics Program (GP2, http://gp2.org/), harmonize clinical data for joint analysis and…Effect of wearing knee braces on unsteadiness on standing in a case with primary orthostatic tremor
Objective: To clarify the effect of wearing knee braces (KB) on unsteadiness on standing in a case with primary orthostatic tremor (OT) using stabilometry and…Neurophysiological and Clinical Effects of Low-intensity Transcranial Ultrasound of the Motor Cortex in Parkinson’s Disease
Objective: Evaluate the neurophysiological and clinical effects of transcranial ultrasound stimulation (TUS) of motor cortex (M1) in PD patients. Background: Low-intensity TUS is a novel,…Cognitive profiles at presentation and subsequent cognitive decline in PD-MCI.
Objective: To determine cognitive profiles in a Parkinson‘s Disease-Mild Cognitive Impairment (PD-MCI) cohort, and study the relationship between baseline cognitive phenotype and subsequent cognitive decline.…Qualification of Digital Endpoints of Function in Healthy Volunteers for Use in a Decentralized Natural History Study in Genetic Parkinson’s Disease (PD)
Objective: Our goal was to qualify digital and wearable devices to assess the Timed Up and Go (TUG) test and gait related parameters in healthy…
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