Administration of the mGlu2 positive allosteric modulator BINA as monotherapy improves parkinsonism in the MPTP-lesioned marmoset
Objective: To assess the effect of selective metabotropic glutamate type 2 (mGlu2) receptor activation on parkinsonism as monotherapy in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned marmoset compared to…Prevalence of sleep disorders in Parkinson’s disease patients at a Brazilian movement disorders center in 2022
Objective: To describe the prevalence of the main sleep disorders in patients with Parkinson's disease at a referral outpatient clinic for movement disorders. Background: Parkinson's…A Man Who Has Been Presenting with Pruritus and Myoclonus
Objective: While various neurological symptoms of sparganosis including have been reported, this is the first documented instance in which sparganosis presented with myoclonus. Background: Sparganosis…DaTscan striatal binding ratio dynamics in mutations carriers at risk for Parkinson’s disease: A 2-year prospective study
Objective: To investigate the temporal dynamics of striatal binding ratios (SBRs) among individuals with Parkinson's disease (PD)-related mutations and its' association with likelihood ratio (LR)…Gait Characteristics from Daily Life Increase Ability to Predict Future Falls in People with Parkinson’s Disease
Objective: We investigated if digital measures of different aspects of gait (walking and turning) from a week of daily activities increase discriminative ability to predict…Anti-α-synuclein antibody 5G4 differentiates idiopathic REM Sleep Behavior Disorder patients from healthy controls in skin biopsies
Objective: The aim of our study was to assess α-synuclein (α-syn) staining using the 5G4 antibody in skin samples of patients with idiopathic REM Sleep…Gait analysis using Wearable Sensors: different gait metrics can differentiate Parkinson’s Disease Patients from Healthy Controls and Parkinson’s Disease patients in different medication status
Objective: To identify which gait metrics better distinguish PD-OFF from PD Best-ON and PD from HC, using a dimensionality-reduction method Background: Objective gait analysis using…Pallidal Deep Brain Stimulation for Treatment of Poststroke Hemichorea
Objective: We report a case of medication-refractory poststroke hemichorea where deep brain stimulation of the globus pallidus internus (GPi-DBS) was utilized to alleviate hemichorea. Background:…Distinct amyloid-dependent patterns of nigral dopamine depletion in Lewy body diseases
Objective: To investigate the effect of amyloid on striatal 18F-FP-CIT uptake patterns in Lewy body disease (LBD), including Parkinson’s disease (PD) and dementia with Lewy…Binaural acoustic stimulation reduces tremor severity in patients suffering from Parkinson’s disease
Objective: To assess the effects of BBS on motor symptoms in PD. Background: Acoustic stimulation (AS) can improve motor symptoms in Parkinson’s disease (PD) and…
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