Axial hypotonia – A pointer towards NBIA – PLA2G6-Associated Neurodegeneration
Objective: While phenotypic spectrum of Neurodegeneration with brain iron accumulation is quite diverse, we discuss a case with peculiar axial hypotonia, a pointer towards PLA2G6…Machine Learning and Instrumented Gait Analysis to Classify Subthalamic DBS States in Parkinson’s Disease
Objective: This study investigates whether gait features derived from an instrumented walk can predict specific treatment conditions (stimulation frequency and medication status) in a cohort…A Phase 2 Randomized, Double-blind, Placebo-controlled Trial of PRAX-944 for the Treatment of Essential Tremor
Objective: Evaluate the tolerability, safety and efficacy of PRAX-944, a selective small molecule T-type calcium channel blocker, for treatment of essential tremor (ET). Background: Essential…Absence of nigrosome as a finding in a patient with suspected atypical parkinsonism.
Objective: Reviewing typical neuroimaging features of the substantia nigra.Noting that the absence of nigrosome 1 has also been seen in atypical parkinsonisms. Background: It is…Contribution of cognitive load to akinetic and trembling freezing of gait manifestations in patients with Parkinson’s disease
Objective: To evaluate the cognitive contribution of a dual task (DT) or motor plan updating while turning on the akinetic and trembling freezing of gait…Longitudinal Analysis of the Corticospinal Tract in Parkinson’s disease Patients
Objective: To assess longitudinal diffusion tensor imaging differences between PD patients in 8 corticospinal tract segments. Background: Parkinson’s disease (PD) is clinically defined by the presence…Relations between subthalamic alpha oscillations and motor control impairment in Parkinson’s Disease patients
Objective: Our goal was to investigate subthalamic movement-related oscillatory dynamics in PD patients with different symptom severity. Background: Stable oscillations at frequencies 8-30 Hz in…Gait ataxia and Autonomic dysfunction as early signs of Creutzfeldt-Jakob Disease: A Case Report
Objective: To highlight unusual early presenting symptoms of Sporadic Creutzfeldt-Jakob Disease (sCJD). Background: Prion diseases, a group of rare and fatal diseases caused by an…HAB-C murine model present reactive adult neurogenesis and astrogliosis in adult brain
Objective: To analyze the adult neurogenic response to a neurodegenerative process due to H-ABC tubulinopathy. Background: H-ABC is a neurodegenerative disease caused by mutations in…4 YEARLONG POST PARTUM AUTOIMMUNE CHOREA AS INITIAL PRESENTATION OF INCOMPLETE SLE/APS
Objective: The aim is to report a case of a 4 yearlong postpartum autoimmune chorea secondary to incomplete SLE/APS. Background: Chorea is a movement disorder…
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