Pharmacological activation of Rev-erbα Provides Neuroprotection against Parkinson’s Disease
Objective: In this study, we investigated the effects of SR9009, a Rev-ERB agonist, on the dopaminergic system in the MPTP model of PD. Background: Circadian…Prevalence of sleep disorders symptoms in essential tremor
Objective: The aim is to study the prevalence of sleep disorders symptoms in patients with essential tremor (ET). Background: ET is the most common movement…NUS1 Mutation Causing Ataxia, Myoclonus, and Progressive Encephalopathy
Objective: Describe a rare cause of progressive myoclonus, ataxia, developmental delay Background: 37-year-old man with normal birth but delays in developmental milestones presented for evaluation…Level of glial neurotrophic factor in the blood plasma depending on the duration of Parkinson’s disease
Objective: To study the level of glial neurotrophic factor in the blood plasma depending on the duration of PD. Background: Study of the biochemical aspects…Collective expert perspectives on the use of safinamide as adjunctive therapy for Parkinson’s disease in Japan: Online-based Delphi approach
Objective: To summarize opinions on the optimal patient profile and methods of using safinamide in common clinical scenarios, Japanese movement disorder specialists with expertise in…Presynaptic dopamine compartmentalization defects initiate auxilin-mediated parkinsonism
Objective: To evaluate the pathogenic mechanisms for auxilin-mediated Parkinson’s disease (PD). Background: Auxilin participates in uncoating of clathrin-coated vesicles (CCVs), thereby facilitating synaptic vesicle (SV)…Glial neurotrophic factor as an early diagnostic marker in Parkinson’s disease
Objective: To study the level of glial neurotrophic disease in blood plasma in patients with Parkinson's disease (PD) Background: Glial neutrophic factor (GDNF) is a…Juvenile Huntington’s Disease in Tunisia: Clinical Diversity and Literature review
Objective: We conducted the first JHD clinical and molecular features in Tunisia and North Africa, contributing to better understanding the diverse manifestation of the disease…Dopaminergic Denervation as Predictors of Axial Dysfunction in Parkinson’s Disease
Objective: We aimed to assess the usefulness of dopamine binding scores as predictors of walking and balance problems and freezing of gait (FoG) in PD.…Discrepancies in postural stability outcomes measured by computerized dynamic posturography and functional balance assessments in Parkinson’s Disease
Objective: To determine ideal assessment for detecting exercise-induced differences in postural stability of individuals with early-stage Parkinson’s Disease (PD). Background: Postural instability (PI) is a…
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