Funding and Sustainability Challenges in Multi-Arm Multi-Stage Clinical Trials in Parkinson Disease
Objective: The Edmond J Safra Accelerating Clinical Trials in Parkinson Disease (PD) initiative (EJS ACT-PD) aims to accelerate the identification of disease modifying treatment for…Video-guided Optimization of Stimulation Settings in Patients with Parkinson’s Disease and Deep Brain Stimulation
Objective: To investigate whether video-based evaluations of motor control and changes of predefined stimulation parameters via patient programmer can improve motor status in Parkinson’s disease…MRI biomarkers of freezing of gait development in in Parkinson’s disease
Objective: This study investigated longitudinal clinical, structural and functional brain alterations in Parkinson’s disease patients with freezing of gait (PD-FoG) and in those developing (PD-FoG-converters)…Frequency of non- motor symptoms in dystonia patients
Objective: Our aim was to see a frequency of non-motor symptoms (NMS) in dystonia patients and influence on quality of life (QoL). Background: Non-motor problems…Amygdala-hippocampus damage critically contributes to visual dysfunction in Parkinson disease
Objective: To delineate the structural and functional alterations of the brain associated with visual dysfunction and retinal injury in Parkinson disease (PD) Background: Several electrophysiological,…Diagnostic yield for point mutation related SCAs through exome sequencing for undetermined ataxias
Objective: To describe the diagnostic yield of whole exome sequencing (WES) to identify autosomal dominant spinocerebellar ataxias (SCAs) caused by point mutations. Background: There are…White Matter Correlates of Physical Therapy Measures in Parkinson’s disease Patients with Freezing of Gait
Objective: To identify white-matter (WM) correlates of physical therapy (PT)-measures in Parkinson’s disease (PD) patients with freezing of gait (FOG). Background: Significant gap remains in…Impact of the dopamine system on long-term, incident cognitive impairment in Parkinson disease
Objective: To determine the impact of the dopamine system (dopamine transporter [DAT] availability, dopamine-related SNPs, and dopaminergic medication use) on long-term cognitive performance in early…A novel compound heterozygous PANK2 gene mutation in a South- Asian sexagenarian with atypical PKAN
Objective: To study the clinical course, imaging and genetics of a case of late-onset dystonia-parkinsonism suspected to have Neurodegeneration with Brain Iron Accumulation (NBIA). Background:…The shaky truth of a Movement Disorder Nurse pilot program in Rural Australia
Objective: The conception of the Movement Disorder Nurse program began when the Australian Government and Fight Parkinson’s conducted a scoping evaluation of people living with…
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