Widening the phenotype of FXTAS in females: Spasmodic dysphonia in two patients
Objective: We present the cases of two female FXTAS patients who both developed spasmodic dysphonia (SD), also known as laryngeal dystonia. Background: Fragile-X-associated tremor/ataxia syndrome…Changes in botulinum toxin dosing in cervical dystonia over 7 years
Objective: To assess changes in botulinum toxin dosing over the course of illness of cervical dystonia. Background: Muscle specific botulinum toxin injections remains the main…Parkinson’s Disease and Psychosocial Impact: Anxiety, Depression and Positive Symptoms
Objective: Explore the relationship between patient self-reported assessment of positive symptoms, depression, and anxiety in PwPD. Background: Parkinson’s disease (PD) is a complex neurodegenerative disorder…SAFINAMIDE: REAL LIFE STUDY. EFFICACY IN SWITCH FROM RASAGILINA AND LOW-DOSE TREATMENT.
Objective: Evaluate the efficacy of safinamide in fluctuations in Parkinson's disease in real life. Analysis by subgroups: Switch rasagiline to safinamide and treatment with low…Safety and Tolerability of Apomorphine Sublingual Film and Subcutaneous Apomorphine for the Treatment of OFF Episodes in Parkinson’s Disease
Objective: Evaluate safety and tolerability of apomorphine sublingual film (SL-APO) vs subcutaneous apomorphine (SC-APO) for the treatment of OFF episodes in patients with Parkinson’s disease…Evolution of biochemical and clinical signature of GBA-related Parkinson’s Disease: a 2-year longitudinal study
Objective: To evaluate peripheral biochemical markers as well as clinical features of GBA-related Parkinson’s Disease (GBA-PD) subjects over a 2-year follow-up in comparison with NM-PD…Exploring the morning akinesia in Parkinson’s disease with the wearable sensor STAT-ON
Objective: To detect the morning akinesia (MA) through the analysis of the gait fluidity (GF) measured by the sensor STAT-ON. Background: The STAT-ON sensor's detection…Comorbidities in Huntington’s disease: An Enroll-HD analysis
Objective: Determine the frequency of comorbidities in people with Huntington’s disease (PwHD) in comparison to non-carrier controls in the Enroll-HD cohort. Background: Despite some publications…A Scoping Review of Multidisciplinary Care in Tourette Syndrome
Objective: To review current multidisciplinary care practices in patients with Tourette syndrome (TS). Background: Individuals with TS can have multiple symptoms and co-morbidities and require…DNA methylation differs between idiopathic Parkinson Disease and Healthy Control subjects in the Parkinson’s Progression Marker Initiative (PPMI) cohort
Objective: Compare baseline whole blood DNA methylation in unmedicated idiopathic Parkinson's Disease (iPD) and healthy control (HC) participants from PPMI Background: Epigenetic mechanisms like DNA…
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