Frequency of non-motor symptoms in GBA-PD may differ in carriers of mild vs. severe pathogenic variants
Objective: Parkinson's disease (PD) patients with pathogenic variants in the GBA (glucocerebrosidase) gene (GBA-PD) were reported to exhibit a younger age at onset, faster progression…Directional DBS – Early experiences with “Current steering” in India
Objective: Deep Brain Stimulation using directional leads is relatively recent in India. We present our early experiences with the same. Background: Deep brain stimulation (DBS)…Longitudinal brain perfusion changes correlated with UPDRS Total in a Phase I mesenchymal stem cell trial for Parkinson’s disease
Objective: Explore changes in correlations between brain perfusion and UPDRS-Total (UPDRS-T) after a single infusion of allogeneic bone marrow-derived mesenchymal stem cells (MSC). Background: Our…Progressive Supranuclear Palsy (PSP) Vs Parkinson’s Disease (PD) – Whether Frontal Assessment Battery (FAB) Can Differentiate
Objective: To find out the ability of the Frontal Assessment Battery (FAB) for quantitative analysis of the executive dysfunction of PSP and PD.To find out…Effects of Parkinson’s disease and freezing of gait on the kinematic and kinetic gait parameters
Objective: This study aims to evaluate the effects of Parkinson's disease and freezing of gait (FoG) on the kinematic and kinetic gait parameters, both in…Optimization of a neuromelanin MRI protocol for use in a longitudinal study of substantia nigra depigmentation in early Parkinson’s Disease (the InsIght-PD study)
Objective: To optimize a neuromelanin-MRI (NM-MRI) protocol for robust and timely change analysis; and acquire serial NM-MRI data in controls and early Parkinson’s Disease (PD),…COMT polymorphism as a genetic factor in levodopa-induced dyskinesia development in Russian patients with Parkinson’s disease
Objective: We examined the influence of single nucleotide polymorphisms (SNPs) in specific genes on levodopa-induced dyskinesia development in Parkinson’s disease patients Background: Levodopa-induced dyskinesia (LID)…Efficacy of Magnetic resonance-guided focused ultrasound thalamotomy (MRgFUS thalamotomy) for refractory essential tremor (ET)-single center experience.
Objective: To assess the efficacy of MRgFUS thalamotomy in patients with ET. Background: MRgFUS thalamotomy can improve tremor in patients with refractory ET[1]. Method: Data…JourneyMap: A visual resource to reduce coordinator burden during virtual study visits
Objective: Reduce burden on research team members and study participants during remote deployment of a touchless sensor device for in-home use with people with Parkinson’s…Reimplantation of the DBS to the patient with generalized dystonia.
Objective: To study the effect of reimplanted DBS after the infection and removing in the cases of 2 dystonia patients in Federal Center of Neurosurgery…
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