Plasma biomarkers of disease progression in Parkinson’s disease
Objective: To identify the ability of a panel of plasma biomarkers to predict disease progression in PD patients Background: Plasma neurofilament light chain (NfL) has…Two cases of severe generalized dystonia in IRF2BPL and response to treatment
Objective: We describe two patients who presented with progressive, generalized dystonia and associated neurodevelopmental regression in early childhood found to have pathogenic variants in IRF2BPL.…Blood neurofilament light chain as a biomarker of Parkinson’s disease
Objective: The objective of the study was to analyse blood neurofilament light chain (NfL) levels in patients with Parkinson’s disease (PD) and healthy controls (HCs),…A fully immersive virtual reality environment to study gait modulation in Parkinson’s disease
Objective: To investigate the safety and efficacy of a fully immersive virtual reality (VR) paradigm to study gait modulation in subjects with Parkinson’s disease (PD).…Diagnosed and Drug-Treated Prevalence of Essential Tremor in Pediatric Patients: Retrospective Analyses of Two US Healthcare Claims Databases
Objective: Estimate the prevalence of diagnosed and drug-treated essential tremor (ET) in the pediatric population using 2 US healthcare claims databases. Background: An ET diagnosis…Using fMRI-based multivariate pattern analysis to differentiate between hyperkinetic movement disorders
Objective: We aimed to investigate differences in functional magnetic resonance imaging (fMRI) brain responses across hyperkinetic movement disorders (HMDs) during a bilateral finger-tapping task.We aimed…Asymmetric midbrain atrophy in a patient with progranulin-related FTLD
Objective: We describe an atypical imaging finding in a patient with corticobasal syndrome (CBS) and a genetic diagnosis of frontotemporal lobar dementia (FTLD) associated with…Longitudinal study of clinical symptoms associated with psychosis in Parkinson’s disease without dementia
Objective: Examine clinical features associated with psychosis among Parkinson’s disease (PD) patients without dementia. Background: Previously identified risk factors for PD psychosis include duration and…Compound heterozygous mutation of the Beta galactosidase 1 gene presenting with familial dystonia and spondylo-epiphyseal dysplasia
Objective: To describe a family with dystonia and spondylo-epiphyseal dysplasia Background: Childhood onset Generalized dystonia is usually associated with genetic causes. Method: We present a…An accurate yet practical method for DBS battery life prediction
Objective: To develop a simple, accurate algorithm for predicting DBS IPG battery life in patients with PD, ET and dystonia. Background: Battery life for DBS…
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