Impaired behavioral proactive inhibitory control and flexibility in a mouse model of early Parkinson’s disease
Objective: The aim of our study is to address the impact of a moderate nigrostriatal DA lesion induced by 6-hydroxydopamine (6-OHDA) injection into the dorsomedial…The USP Project: Understanding the Scope and Value of Parkinson’s Specialist Nursing
Objective: This paper will present evidence from the first stakeholder-driven UK study to explore in-depth the role and value of the Parkinson’s Nurse Specialist (PNS)…Natural progression of patients with Parkinson disease on less pulsatile levodopa therapy
Objective: To evaluate the natural progression of Parkinson disease (PD) in patients on less pulsatile levodopa therapy (LPT). Background: Previously we have shown that patients…Vascular Causes of Atypical Parkinsonism Versus Vascular Contribution Towards Atypical Parkinsonism
Objective: In this study, we have compared the clinical features of atypical parkinsonism with high vascular load to find the difference between isolated vascular pathology…Time reproduction in Parkinson’s disease: Is there a specific impairment in context of movements?
Objective: Investigating the reproduction of time intervals in context of a motor imagery task in Parkinson’s disease Background: In Parkinson’s disease (PD), impaired perception of…Impaired reinforcement learning in patients with cerebellar ataxia
Objective: To further characterize cerebellar learning processes as well as learning impairment pattern in patients with cerebellar dysfunction. Background: Supervised learning (i.e., learning from error)…A mouse model to test the cortical pathogenic theory of Parkinson’s disease
Objective: To develop a mouse model of chronic corticostriatal overactivity and increase expression of corticostriatal alpha-synuclein. Background: Parkinson’s disease typically has a focal motor onset1,…Neurodegeneration and neuroinflammation for biomarker development in MSA
Objective: To investigate the diagnostic and prognostic value of fluid-based and PET imaging biomarkers related to neurodegeneration and neuroinflammation in Multiple System Atrophy (MSA). Background:…Excessive tearing; a paradoxical ocular manifestation of Parkinson’s disease
Objective: To demonstrate a case report of excessive tearing in Parkinson’s disease patient Background: Dry eye is the common ocular manifestations in PD patients. The…Alteration of peripheral blood cell profiles in Parkinson’s disease: a retrospective case-control study
Objective: The aim of this study is to investigate the relationship between peripheral blood cell profiles and Parkinson's disease (PD). Background: Abnormal immune response and systemic inflammation have…
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