Baseline Characteristics and Treatment Patterns of a Global Huntington Disease Population Stratified by Chorea Severity
Objective: To describe baseline characteristics and treatment patterns in patients with chorea associated with Huntington disease (HD) by severity of chorea. Background: Though multiple treatment…Sex Modulates Cognitive Association of Lewy Body Pathology
Objective: To assess whether the association between Lewy body (LB) pathology stages and cognition differs for women and men Background: Progression of LB pathology is…Environmental exposures and clinical phenotype in a sample of patients with Parkinson’s disease in the southwestern Colombian region: preliminary results
Objective: Describe the clinical phenotype and environmental agents of patients from the Colombian southwestern region with familiar and sporadic Parkinson’s disease in a sample Background:…Prevalence of Parkinson’s disease and Atypical Parkinsonisms in Colombia: Data from the national health registry 2016-2021
Objective: To estimate prevalence of Parkinson’s Disease (PD) and Atypical Parkinsonisms and characterise the diagnosed population in a country with a development economy Background: The…Diagnostic algorithm in recessive and sporadic early-onset ataxias
Objective: To develop a diagnostic algorithm that allows to differentiate recessive or sporadic ataxias by the clinical phenotype, biochemical markers and neuroimaging studies of the…Evaluation of α-synuclein pathology and function in dopaminergic neurons derived from LRRK2 I1371V PD patient iPSCs
Objective: To evaluate cellular pathogenesis in DA neuron function, and α-synuclein pathology using LRRK2-I1371V PD iPSC. Background: It is reported for complex-neurodegenerative disorders like PD,…Protective approach targeting NF-kB/ Nrf2 signaling and neuroinflammation using Apigenin in LPS induced Parkinsonism in experimental rats
Objective: 1. Apigenin as a protective strategy to prevent neuroinflammation in PD.2. To find behavioral, neurochemical and histopathological changes in LPS induced PD. Background: Parkinson’s…A rare case of Hyperkinetic Movement disorder
Objective: We present a case of hyperkinetic movement disorder in a 47 year old male with 3 year history of behavioural changes, chorea and dystonia…Melatonin attenuates the bidirectional Gut-Brain axis mediated inflammation caused by Ambient Particulate Matter (PM2.5) and averts neurodegeneration
Objective: To explore the therapeutic potential of melatonin in attenuating the PM2.5 induced inflammation and neurodegeneration through the Gut-brain axis in C57BL/6 mice. Background: The…Three patients with PSP presenting with a logopenic pattern of aphasia: expanding the phenotype of language impairment in PSP.
Objective: To investigate the a series of cases presenting with apparent logopenic variant primary progressive aphasia who then developed symptoms suggestive of PSP. Background: Deficits…
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