Akinetic-rigid motor presentation among adult-onset HD participants in Enroll-HD
Objective: To characterize a variant of adult Huntington’s disease (HD) with akinetic-rigid syndrome (ARS) as initial motor manifestation Background: HD Cases have been reported with…In vivo relationship between synaptic density and functional connectivity in progressive supranuclear palsy: a multimodal [11C]UCB-J PET and resting state fMRI study.
Objective: To assess the relationship between synaptic density and functional connectivity in the primary tauopathy of Progressive Supranuclear Palsy (PSP). Background: PSP is a debilitating…Tinospora Cordifolia protects against Rotenone induced degeneration of dopaminergic neurons in mouse model of Parkinson’s disease
Objective: To explore the neuroprotective mechanisms of T. cordifolia ethanolic extract against Rotenone (ROT)-intoxicated mouse model through proteomics approach. Background: The death of dopaminergic (DAergic)…The role of community engagement and involvement in Parkinson’s disease research: a case study from Africa
Objective: Using a case study from Africa to understand the potential role of community engagement and involvement (CEI) in future research on Parkinson’s disease (PD).…Does Macronutrient dietary Intake of patients with Parkinson disease correlates with the cognitive function (MoCA)?
Objective: Analyze the correlation between macronutrient dietary intake and cognitive function of patients with Parkinson’s Disease Background: Several studies have shown that implementing a healthy…Movement disorders in demyelination: A case series of ten patients
Objective: To observe the association of various movement disorder with demyelinating disease. Background: Movement disorders in demyelinating diseases are not an unheard entity, but besides…Evaluating palliative care needs in patients with Parkinson’s disease and related disorders
Objective: To assess the palliative care needs in patients with Parkinson’s disease and related disorders at an academic movement disorders clinic. Background: There is growing…The OASIS (OpicApone in Sleep dISorder) study in Parkinson’s disease: design and rationale of an open-label, single-arm, pilot trial
Objective: To evaluate the effects of opicapone (OPC) treatment on sleep disorders in patients with Parkinson’s disease (PD) and ‘wearing-off’. Background: OPC proved to be…Azathioprine immunosuppression and disease modification in Parkinson’s disease (AZA-PD): a randomised double-blind placebo-controlled phase II clinical trial
Objective: To design a clinical trial to test the concept that the immune system is integral in the progression of Parkinson’s disease (PD) and establish…Cinpanemab in Early Parkinson’s Disease: Phase 2 SPARK Study Results
Objective: To evaluate cinpanemab (BIIB054) efficacy and safety. Background: Aggregated alpha-synuclein (α-syn), a major constituent of Lewy bodies, is thought to play a central role…
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