“Striatal Hand Signs” and early diagnosis of Parkinson’s Disease: The “Monkey-Wrench Sign”.
Objective: To identify signs of hand deformations in PD patients with earlier diseases, and compare with intermediate and late phases patients. Background: “Striatal hand signs”,…Cardiovascular risk factors and phenoconversion to neurodegenerative synucleinopathies in idiopathic REM sleep behavior disorder
Objective: To evaluate the predictive role of cardiovascular diseases and metabolic risk factors in the phenoconversion of idiopathic REM sleep behavior disorder (iRBD) patients. Background:…Associations between Baseline Cognitive Function and Gait Outcomes after Treadmill Training in Parkinson’s disease
Objective: To determine the effect of baseline cognition on gait outcomes after a gait training and aerobic exercise program in people with Parkinson's disease (PD).…Encoding, consolidation, and retrieval performance in memory tasks of MCI and n-MCI patients with Parkinson’s Disease.
Objective: Quantify and compare encoding, consolidation, and retrieval performance in verbal and visual memory tasks in MCI and Non-MCI Parkinson's disease. Background: Parkinson’s Disease (PD)…Low dose trihexyphenidyl use causes cognitive dysfunction in Parkinson’s disease patients.
Objective: Evaluate cognitive performance in Parkinson's disease patients receiving a low dose of trihexyphenidyl (THP). Background: Before L-Dopa's discovery, anticholinergic drugs were among the first…Identification of a new Homozygous mutation P.R258Q In the gene SYNJ1 of an Algerian consanguine (inbred) Family suffering from early onset atypical Parkinsonism
Objective: The purpose of this observation is to demonstrate that autosomal recessive early parkinsonism is clinically and genetically heterogeneous Background: Early Onset Parkinson’s disease is…Novel PLA2G6 Mutation Presenting as Early-Onset Parkinson’s Disease
Objective: To report a case of a novel mutation in the PLA2G6 gene resulting in early-onset Parkinson’s Disease. Background: The phospholipase A2 group VI (PLA2G6)…Glucocerebrosidase activity does not predict Parkinson’s Disease risk or severity
Objective: To explore the association between GCase activity, PD phenotype and probability for prodromal PD among PD and non-manifesting carriers (NMC) of mutations in the…Parkinson’s Families Project: analysis of a large cohort of patients with early onset and familial Parkinson’s disease
Objective: We aim to identify new gene variants associated with familial and early-onset Parkinson's disease (PD), through genetic comparison of affected and unaffected family members.…Plasma and fecal short chain fatty acids as predictors for the risk and severity of Parkinson’s Disease
Objective: To delineate the influence of plasma and fecal short chain fatty acids (SCFAs) on the risk and severity of Parkinson’s disease (PD). Background: Recent…
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