Long-Term Motor Function and Quality of Life Outcomes from a Prospective, International DBS Registry
Objective: To report the outcomes of an ongoing prospective, international, large-scale registry of Deep Brain Stimulation (DBS) systems for Parkinson’s Disease. Background: Several studies have…Autoimmunity may contribute to peri-electrode edema after deep brain stimulation for Parkinson’s disease: a case series
Objective: To identify and characterize cases of symptomatic peri-electrode edema after DBS. Background: Peri-electrode edema is a rare complication of Deep Brain Stimulation (DBS) surgery.…Utilizing digital biomarkers to explore risk factors for falls in patients with Lewy Body Dementia
Objective: To analyze risk factors for falls in individuals with Lewy Body Dementia (LBD) enrolled in PRESENCE. Background: PRESENCE was a phase 2 clinical trial…Validity of quantitative parameters for analyzing gait motion in PD patients after STN-DBS
Objective: The validity of parameters for quantitative assessment of gait movement characteristics specific to Parkinson's disease (PD) patients was tested with data from STN-DBS On/Off.…Normative data for six standardized motor tasks in healthy adults
Objective: To determine range and variance for spatiotemporal parameters from a short motor test battery using depth sensing technology. Background: Emerging instrumented motion analysis systems…Persistent and efficient transduction of the putamen following gene therapy for aromatic L-amino acid decarboxylase deficiency
Objective: This study aimed to evaluate longitudinal transduction in subcortical regions and transduction of the cortico-putaminal network after putaminal AADC gene therapy. Background: Aromatic L-amino…Impact of Covid-19 on Essential Tremor and Dystonic Tremor: experience of an Italian centre
Objective: To assess the impact of Covid-19 on Essential and Dystonic Tremor, with regard on non-motor symptoms, social aspects and everyday life. Background: Covid-19 had…Automated analysis of pen-on-paper spirals for tremor detection, quantification and differentiation
Objective: To develop and validate an automated analysis algorithm for pen-on-paper Archimedes spirals. Background: Spiral drawings are used in the clinic to identify and quantify…Are physiotherapists reliable in their scoring of freezing of gait?
Objective: To determine the reliability of freezing of gait scoring through post-hoc video analysis in raters with a physiotherapy background. Background: Freezing of gait affects…Data-driven model of dynamic biomarkers in SCA3 – from early pre-ataxic to late ataxic disease stages
Objective: The aim was to establish a data-driven model of dynamic biomarkers in SCA3 from the early pre-ataxic to the late ataxic disease stage. Background:…
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