Non-motor symptoms in Parkinson’s disease
Objective: The objective of our study is to assess the prevalence of non motor signs in patients with parkinson’s disease and to propose an adapted…Dual-task interference on weight-shifting in Parkinson’s Disease with freezing of gait and without freezing of gait
Objective: To investigate the control of dual-task weight-shifting in Parkinson's disease (PD) with freezing of gait (FOG) and without FOG). Background: With more impairment in…Cuneiform Nucleus Deep Brain Stimulation for Freezing of Gait in Parkinson’s disease. Initial clinical report.
Objective: Here we report a first in human targeting of Cuneiform Nucleus (CnF) using MR tractography, observation of intraoperative stimulation patterns and stimulation precision benefits of…A Phase 2 Randomized Controlled Trial Repurposing Ambroxol as a Disease Modifying Treatment for Parkinson’s Disease Dementia.
Objective: Currently there are no disease-treatments for Synucleinopathies including Parkinson’s disease dementia (PDD). Our objective is to use Ambroxol to target GBA/Glucocerebrosidase to treat PDD.…Secondary endpoints of a randomized, placebo-Controlled Pilot Study to evaluate the safety of lyophilized PRIM-DJ2727 in Parkinson’s disease
Objective: To evaluate the impact of fecal microbiome transplant (FMT) on disease progression as a secondary outcome of a safety study using PRIM-DJ2727 in Parkinson's…The effect of medical xenon on patients with advanced stages of the Parkinson’s disease with motor fluctuations
Objective: The aim of the study to increase the effectiveness of pharmacotherapy in patients with advanced stages of Parkinson's disease (PD) with motor fluctuations, using…Classification of Advanced Parkinson’s Disease in OBSERVE-PD Patients Based on the MANAGE-PD Screening Tool
Objective: This post-hoc analysis evaluated uncontrolled patients from OBSERVE-PD identified as advanced Parkinson’s disease (APD) based on domains evaluated in section 2 of the MANAGE-PD…IS THE HYPOXIA EXPOSURE BENEFICIAL FOR PEOPLE WITH PARKINSON’S DISEASE? A SCOPE REVIEW
Objective: To explore the current evidence and identify knowledge gaps, we conducted a scoping review about the hypoxia exposure effects on people with Parkinson’s disease…Opicapone in Parkinson’s disease patients with early/simple motor fluctuations: real-world Spanish data
Objective: To evaluate the efficacy and tolerability of opicapone in patients in Parkinson’s disease (PD) patients with early/simple motor fluctuations (E/S-MF) in the Spanish clinical…Parkinson’s Disease Medication Safety in the Inpatient Cohort of a Tertiary Centre
Objective: Our study aimed to determine the accuracy of initial prescribing on hospital admission and the subsequent timing of administration of Parkinson’s disease (PD) medications…
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