Prevalence of Suicidal Ideation and Associated Clinical Features in Lewy Body Dementia
Objective: The goal of this study was to identify the prevalence of suicidal ideation (SI) in Lewy body dementia (LBD) and the factors associated with…ASSOCIATION BETWEEN INSULIN RESISTANCE AND DEVELOPMENT OF DEMENTIA IN PATIENTS WITH PARKINSON´S DISEASE
Objective: The main objective of the study was to analyze the association between insulin resistance (IR ) at diagnosis and the development of dementia in…Reduced Alpha suppression & altered EEG signal complexity in Parkinson’s disease – signatures of cognitive impairment?
Objective: In a cross-sectional setting both alpha suppression and complexity of alpha-band oscillations are evaluated as diagnostic biomarker for assessing MCI in early stages of…Falls in Parkinson’s Disease: The Impact of Cognitive Performance
Objective: This study aimed to assess the incidence of falls in a population of PD patients and their clinical performance on cognitive assessment scales. Background:…Parkinson’s-disease risk variants are differentially associated with discrete phenotypic characteristics of Parkinson’s-disease at baseline.
Objective: Evaluate whether genetic risk variants for Parkinson’s disease discovered in case-control GWAS uniformly or differentially contribute to the clinical phenotype of PD. Background: Genetic…SHBG, and possibly testosterone, are associated with the risk for Parkinson’s disease among women: a Mendelian randomization approach
Objective: To assess the association between Sex Hormone Binding Globulin (SHBG), Testosterone, and Estradiol with Parkinson's disease (PD). Background: Sex hormones may protect dopaminergic neurons,…Ultrastructural Characterization of Monocytes in Parkinson’s Disease and GBA mutations
Objective: To identify morphological changes in circulating CD14+ monocytes in manifesting and non-manifesting carriers of mutations of the GBA gene and Parkinson’s disease (PD). Background: Mutations of…The MJFF Global Genetic Parkinson’s Disease Research Resource
Objective: To establish a comprehensive research and clinical trial-ready resource of centers working with individuals with monogenic Parkinson’s Disease (PD). Background: As gene-targeted therapies are…CHARACTERIZATION OF LRP10 EXPRESSION IN LEWY BODY DISORDERS AND IPSC-DERIVED BRAIN CELLS
Objective: Our objective is to characterize endogenous low-density lipoprotein-related protein 10 (LRP10) expression in human induced pluripotent stem cell (iPSC)-derived brain cell types, post-mortem brain…The Role Imposed by The High-Mobility Group Box 1 (HMGB1) Protein in MPTP-Induced Zebrafish Model of Parkinson’s Disease
Objective: This study aims to investigate the role of HMGB1 protein in mediating neuroinflammatory-induced parkinsonian movement disorder of the MPTP-induced zebrafish model of Parkinson's disease…
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