Double labeling alpha-synuclein in labial minor salivary glands in Parkinson’s disease and idiopathic RBD patients
Objective: To investigate the presence of α-Syn immunostaining in minor salivary gland biopsies (MSGB) from patients with idiopathic Parkinson's disease (PD), idiopathic Rapid Eye Movement…Functional connectivity as an early marker of indication for deep brain stimulation treatment in Parkinson’s disease (PD)
Objective: To identify functional neuroimaging patterns anticipating the clinical indication for deep brain stimulation (DBS) in patients with PD. Background: DBS has become a well-established…Resting-state connectivity predictors for prefrontal cortex activity during walking in Parkinson’s disease.
Objective: Investigating whether resting-state brain connectivity can predict prefrontal cortex activity (PFCA) during walking for patients with Parkinson's disease (PD) and reflect the benefits of…Longitudinal changes in nigral neuromelanin in early, levodopa-treated Parkinson’s disease
Objective: To assess longitudinal changes in neuromelanin (NM) content in the substantia nigra compacta (SNc) and its lateral-ventral subregion in Parkinson’s disease (PD). Background: NM-sensitive…DAT-SPECT in old onset Parkinson’s disease: should we trust?
Objective: . Background: Scans without evidence of dopaminergic deficit (SWEDD) refers to patients clinically diagnosed with Parkinson’s disease (PD), but show normal findings on dopamine…Progression of nigrostriatal dysfunction in Parkinson’s disease: a longitudinal multimodal PET study
Objective: To investigate the longitudinal course of nigrostriatal metabolic and dopaminergic dysfunction and its impact on symptom severity in Parkinson's disease (PD) patients using a…Longitudinal Study of Grey Matter Nuclei in Early Parkinson’s Disease using Diffusion Kurtosis Imaging
Objective: We aimed to determine whether microstructural characteristics of key grey matter nuclei would be differentially altered between baseline and two-year timepoints in Parkinson’s disease…Emotional stress exacerbates parkinsonian resting tremor
Objective: To examine the role emotions may play in modulating the characteristics of parkinsonian resting tremor. Background: There is ample evidence showing cognitive stress can…Influence of Levodopa on Archimedes Spiral Drawings in Idiopathic Parkinson’s Disease
Objective: To study the effects of levodopa on Archimedes spiral drawings by idiopathic Parkinson’s Disease (PD) patients. Background: Handwriting difficulty can develop as an early…Lateralization of cochlear dysfunction as a specific biomarker of Parkinson’s disease; role for cholinergic transmission?
Objective: To understand to what extent an early cochlear dysfunction may represent an additional non-motor signature of Parkinson’s disease (PD) patients. Further, whether it may…
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