Locus coeruleus degeneration associated with less levodopa responsiveness in Parkinson’s Disease
Objective: We aimed to explore the relationship between LC degeneration and levodopa responsiveness in Parkinson’s Disease (PD) patients in vivo. Background: Widely divergent responsiveness of…Long-term effect of safinamide on primary motor cortex excitability and plasticity in Parkinson’s disease: a TMS study
Objective: To examine the long-term effect of chronic treatment with safinamide 100 mg/day on specific Transcranial Magnetic Stimulation (TMS) measures of primary motor cortex (M1)…Abnormalities of vestibular-evoked myogenic potentials are associated with REM sleep without atonia in early Parkinson’s disease and idiopathic REM sleep behavior disorder
Objective: To explore the brainstem lesion reflected by means of vestibular-evoked myogenic potentials(VEMPs) and its association with REM sleep without atonia(RSWA) and other clinical assessments…Autonomic dysfunction in patients with Parkinson’s disease
Objective: Discuss the prevalence, clinical manifestations, and impact of autonomic dysfunction in Parkinson's disease (PD). Background: Autonomic dysfunction is an important non-motor feature of PD…Anxiety and depression in patients with Parkinson’s disease selected for magnetic resonance-guided focused ultrasound thalamotomy.
Objective: To assess the severity of anxiety and depression in patients selected for treatment with the magnetic resonance-guided focused ultrasound thalamotomy (MRgFUS TT) before the…What predicts RBD in PD patients: video-polysomnographycally supported data from advanced, fluctuating Parkinson’s disease?
Objective: We aimed to identify factors that predict the occurrence of REM Sleep Behaviour disorder (RBD) in Parkinson’s Disease (PD) patients by modelling data from…Predictors of Clinically Significant Quality of Life Impairment in Parkinson´s Disease. Results from the COPPADIS Cohort at 2 Years Follow-up.
Objective: The aim of the present study was to identify predictors of clinically significant quality of life (QoL) impairment in Parkinson´s disease (PD) patients from…Smell dysfunction correlates with severity of motor deficits in H&Y stage-I early onset Parkinson’s disease
Objective: The objective of this study is to test the hypotheses that: 1) olfactory dysfunction in early stage Parkinson’s disease (PD) is correlated with severity…Sphingosine-1-phosphate, motor severity and progression in Parkinson’s disease (MARK-PD)
Objective: We assessed the association of serum sphingosine-1-phosphate (S1P) levels with motor and cognitive symptoms in patients with Parkinson’s disease (PD). Background: Treatment with sphingosine-1-phosphate…Daily fluctuations of plasma ghrelin level in patients with different motor subtypes of Parkinson`s disease
Objective: The objective of this study is to compare evening and morning plasma ghrelin level in patients with different motor subtypes of Parkinson`s disease (PD).…
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