The PD-1102 trial in advanced Parkinson’s disease: safety and clinical outcomes from a 3-year phase 1b study of AADC gene therapy administered via a posterior approach
Objective: To present 3-year safety and clinical outcome data from a phase 1b, open-label trial of VY-AADC01 (NBIb-1817) for Parkinson’s disease (PD) patients with motor…Effectiveness of opicapone in Parkinson’s disease patients with motor fluctuations according to baseline use of entacapone: findings from the real-world OPTIPARK study
Objective: This post-hoc analysis evaluated the effectiveness of opicapone (OPC) in Parkinson’s disease (PD) patients with motor fluctuations (MF) according to baseline use of entacapone…OPTIMIPARK Questionnaire:a tool to optimize treatment in Parkinson´s disease.
Objective: To validate the OPTIMIPARK questionnaire as a tool to help the clinician in the adjustment of dopaminergic treatment in Parkinson´s disease(PD). Background: At early…Effectiveness of opicapone in Parkinson’s disease patients with motor fluctuations according to baseline use of safinamide: findings from the real-world OPTIPARK study
Objective: This post-hoc analysis evaluated the effectiveness of opicapone (OPC) in Parkinson’s disease (PD) patients with motor fluctuations (MF) according to baseline use of safinamide…The Transcriptome from Multiple Regions of the MPTP-induced Parkinson’s disease Mouse Brain after exercise
Objective: To illuminate the respective functions of substantia nigra, striatum, cortex and cerebellum in Parkinson's motor improvement following exercise training in a chronic MPD (MPTP…Cognitive assessment in a Greek cohort of Multiple System Atrophy patients.
Objective: The aim of the present study was to assess cognitive dysfunction in a Multiple System Atrophy (MSA) cohort and possible differences between disorder subtypes…Fatigue in patients with progressive supranuclear palsy
Objective: To investigate prevalence and clinical impact of fatigue in the patients with progressive supranuclear palsy Background: Fatigue is a common and disabling non-motor symptom…Quantitative susceptibility mapping and blood neurofilament light chain differentiate between parkinsonian disorders
Objective: We employed Quantitative susceptibility mapping (QSM) to assess iron deposition in a larger sample size and explore whether combining QSM and NfL can improve…EPIDEMIOLOGICAL OVERVIEW OF PARKINSON’S DISEASE IN BRAZIL
Objective: To describe the epidemiological profile in patients hospitalized with Parkinson's Disease in Brazil during the years 2015 to 2020. Background: Parkinson's disease (PD) is…A case of dystonia-parkinsonism associated with a heterozygous PRKRA (DYT16) gene mutation
Objective: We describe the clinical presentation, diagnosis, and treatment of a case of dystonia-parkinsonism associated with a heterozygous mutation in the initiator methionine of the…
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