MDS Translation Program for MDS-UPDRS, UDysRS, and MDS-NMS
Objective: To summarize the status of the ongoing MDS-sponsored translation programs for non-English versions of the MDS-UPDRS, UDysRS, and MDS-NMS. Background: The MDS-UPDRS, UDysRS, and…Metabolic patterns and neurodegeneration in isolated REM sleep behavior disorder
Objective: To elucidate the role of Parkinson’s disease (PD)-related brain metabolic patterns as a biomarker in isolated rapid-eye-movement sleep behavior disorder (iRBD) for clinical correlation…DEEP BRAIN STIMULATION RESPONSE IN SIBLINGS WITH KMT2B DYSTONIA
Objective: To report two cases of adult-onset KMT2B related dystonia treated with pallidal deep brain stimulation (DBS). Background: KMT2B gene mutations have been described as…Subthalamic nucleus deep brain stimulation implant hemisphere differentially changes verbal fluency in patients with Parkinson disease
Objective: To investigate verbal fluency following unilateral subthalamic nucleus (STN) deep brain stimulation (DBS) in patients with Parkinson’s disease (PD). Background: Verbal fluency declines in…MRgFUS Pallidothalamic Tractotomy for axial symptoms in Parkinson’s disease in 4 consecutive patients: single center experience
Objective: We aimed at demonstrating the efficacy profile of MRgFUS pallidothalamic tractotomy (PTT) against the axial symptoms of Parkinson's disease. Background: Ablative neurosurgery on the…The feasibility and efficacy of virtual visits compared to in-person visits for follow up in Parkinson´s disease: methodology for an international, multicenter trial (NCT04695353).
Objective: To investigate the feasibility and efficacy of virtual visits for Parkinson Disease (PD) compared to in-person visits. Background: Considering limited access to specialists for…A Machine Learning Approach to VTA Prediction in DBS
Objective: This study aims to evaluate a novel, machine learning approach to volume of activation (VTA) prediction for real-time use in the clinical setting and…Feasibility to Detect Parkinson’s Motor Symptoms with a Waist-Worn Parkinson’s Holter
Objective: Analysis of the feasibility in the detection of Parkinson’s Motor Symptoms. Background: Usually, in current clinical practice, the physicians have a very limited slot…Tissue-engineered nigrostriatal pathway to rebuild dopaminergic axons in Parkinson’s disease based on clinical design criteria
Objective: To create a tissue-engineered construct with the dopaminergic (DA) cell numbers, axon lengths, and functionality required to reconstruct the human nigrostriatal pathway (NSP). Background:…Deep brain stimulation for Orthostatic Tremor
Objective: 1) To evaluate the effect of deep brain stimulation (DBS) in Orthostatic Tremor (OT) on standing time and quality of life (QoL), and 2)…
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