Spinocerebellar ataxia (SCA) type 2 and type 8: a tale of two repeat expansions in a single patient
Objective: To describe the rare occurrence of coexisting SCA Types 2 and 8 in a pediatric patient. Background: SCAs are a group of autosomal dominant…Reversible hemichorea due to contralateral anterior cerebral artery territory hypoperfusion
Objective: We report hemichorea due to hypoperfusion of the contralateral anterior cerebral artery (ACA) territory (including caudate nucleus and its connections) that reversed with revascularization.…Pilot study to evaluate pimavanserin for the treatment of motor and behavioral symptoms of Tourette syndrome.
Objective: To determine whether pimavanserin has an effect on motor and behavioral aspects of Tourette syndrome (TS). Background: Pimavanserin is a serotonin 2A receptor inverse…Carboplatin, Paclitaxel, and Nivolumab-induced Parkinsonism Responsive to Levodopa
Objective: To present the first reported case of reversible, levodopa sensitive, chemotherapy- induced parkinsonism due to the combination of carboplatin, paclitaxel, and nivolumab. Background: Many case reports describe antineoplastic agents causing reversible parkinsonism, most commonly, cyclophosphamide, cytosine arabinoside, and cyclosporine. To our knowledge, drug-induced parkinsonism related to combination therapy of paclitaxel, carboplatin, and nivolumab has never been…A Phase 3 Trial Evaluating the Efficacy, Duration of Effect, and Safety of DaxibotulinumtoxinA for Injection in the Treatment of Cervical Dystonia
Objective: To evaluate the efficacy and safety of two doses of DaxibotulinumtoxinA for Injection (DAXI) vs placebo for treatment of cervical dystonia (CD). Background: DAXI…Analysis of dystonia and rating scales in children and young adults with SGCE myoclonus dystonia
Objective: The aim of this study was to analyze the clinical characteristics of dystonia (Axis I) and to explore rating tools for writing, walking and running…Diagnosis and management of Myoclonus Dystonia Syndrome: a Survey of the European Reference Network for Rare Neurological Diseases.
Objective: To evaluate the diagnostic and treatment strategies in Myoclonus Dystonia Syndrome (MDS) used by experts from the European Reference Network for rare neurological diseases…Neural Signals in the Cerebellar Nuclei Gate the Manifestation of Dystonia-Associated Symptoms in Mice
Objective: Define the differences in electrophysiological signatures of cerebellar output between mouse models of dystonia with diverse severity and manifestation. Background: Dystonia is heterogeneous movement…Patterns and determinants of healthcare utilization among people with Parkinson’s disease: A population based analysis in Ontario, Canada
Objective: To identify spatial patterns of healthcare utilization among people with Parkinson’s disease (PwP) and examine factors associated with individuals’ observed access-to-care in Ontario. Background:…The COVID-19 Pandemic Impact on Advanced Parkinson’s Disease in the US
Objective: Characterize the risk of seven acute medical events in persons with advanced Parkinson’s disease (PD) using real world data before and within 12 months…
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