MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    Extensive volume increases sensitivity of alpha-synuclein accumulation in the gastrointestinal tract

    C. Shin, SI. Kim, SH. Park, HJ. Kim, B. Jeon (Sejong-Si, Republic of Korea)

    Objective: This study aimed to verify whether evaluation of extensive tissue volume increases sensitivity of detecting alpha-synuclein (AS) pathology in the gastrointestinal (GI) tract in…
  • MDS Virtual Congress 2021

    Long-term cognitive and motor decline across the spectrum of Lewy body disease.

    MC. Gonzalez, J. Maple-Grødem, D. Tovar‐rios, CH. Williams-Gray, M. Camacho, L. Forsgren, D. Bäckström, R. Lawson, AD. Macleod, CE. Counsell, C. Paquet, C. Falup-Pecurariu, F. Blanc, A. Padovani, C. de Lena, F. D'Antonio, G. Alves, D. Aarsland (Stavanger, Norway)

    Objective: This study aims to compare the progression of motor and cognitive decline in dementia with Lewy bodies (DLB) compared with Parkinson’s disease (PD) using…
  • MDS Virtual Congress 2021

    AMP PD: Collaborating in the discovery of biomarkers to accelerate the development of therapies for Parkinson’s disease

    C. Swanson-Fischer, E. Appelmans, D. Babcock, M. Bookman, D. Alonso, L. Kirsch, C. Wonders, J. Ward, S. Biswas, S. Dey, A. Singleton, H. Iwaki (North Bethesda, USA)

    Objective: The Accelerating Medicines Partnership in Parkinson’s Disease (AMP PD; https://amp-pd.org) aims to identify and validate diagnostic, prognostic, and progression biomarkers for Parkinson’s Disease (PD).…
  • MDS Virtual Congress 2021

    Motor skills of walking in Parkinson’s disease: towards a better understanding of the cognitive abilities implicated in F8WT.

    V. Cian, M. Zarucchi, C. Siri, A. Giobbia, P. Ortelli, G. Frazzitta, M. Canesi (Gravedona Ed Uniti, Italy)

    Objective: to evaluate disease related and cognitive features involved in motor skills of walking in people with Parkinson’s disease (PWP). Background: curved path walking and…
  • MDS Virtual Congress 2021

    Sex-Specific White Matter Correlates of Neuropsychological Measures in Parkinson’s disease with Mild Cognitive Impairment

    V. Mishra, K. Sreenivasan, D. Cordes, A. Ritter, Z. Mari, J. Caldwell (Las Vegas, USA)

    Objective: To identify sex-specific white-matter (WM) correlates of neuropsychological measures in Parkinson’s disease (PD) with mild cognitive impairment (MCI). Background: Neuropsychological measures of executive function…
  • MDS Virtual Congress 2021

    A prospective study of Parkinson’s disease progression towards dementia – dynamics and defining motor features

    T. Stojkovic, LJ. Ziropadja, E. Stefanova, V. Markovic, I. Stankovic, I. Petrovic, N. Dragasevic Miskovic, M. Svetel, V. Kostic (Belgrade, Serbia)

    Objective: Our goal was to investigate the rate of progression to dementia (PDD) in our cohort of Parkinson’s disease (PD) patients and to explore how…
  • MDS Virtual Congress 2021

    Genotypic and phenotypic spectrum of PINK-1 associated parkinsonism in 44 mutation carriers from 11 Tunisian families

    G. El Fessi, Z. Saied, F. Nebli, M. Zouari, S. Belal, S. Ben Sassi (Tunis, Tunisia)

    Objective: To characterize the family history and clinical features of mutations of the PINK-1 gene in a cohort of Tunisian patients with Parkinson disease (P.D)…
  • MDS Virtual Congress 2021

    Rare Neurodegenerative Phenotypes in Patients Carrying Homozygous GBA1 Mutations

    G. Lopez, N. Tayebi, M. Hallett, A. Zimran, P. Kishnani, E. Sidransky (Bethesda, USA)

    Objective: To describe patients with Type 1 Gaucher disease who developed a rare neurodegenerative disease other than synucleinopathies. Background: Lysosomal dysfunction as a contributor to…
  • MDS Virtual Congress 2021

    Remote assessment of prodromal Parkinson’s disease in a LRRK2 G2019S cohort

    J. Soto, S. Jensen-Roberts, T. Meyers, M. Pawlik, J. Moore, A. Sarkar, R. Wilson, P. Auinger, E. Dorsey, B. Valdovinos, K. Amodeo, S. Sharma, R. Holloway, H. Rowbotham, E. Chanoff, P. Cannon, R. Alcalay, R. Schneider (Rochester, USA)

    Objective: To compare remote application of the Movement Disorder Society (MDS) prodromal Parkinson’s disease (PD) criteria to expert clinical determination of possible parkinsonism in a…
  • MDS Virtual Congress 2021

    Integrated Multi-omics of the Gut Microbiome Reveal 2-Hydroxypyridine as a Novel Molecule Relevant to Parkinson’s Disease Pathogenesis

    V. Aho, JP. Trezzi, C. Jäger, S. Schade, C. Trenkwalder, A. Janzen, U. Heins-Marroquin, C. Linster, G. Gomez Giro, J. Schwamborn, T. Kitami, M. Thomas, K. Schmit, C. Martin-Gallausiaux, M. Buttini, M. Mittelbronn, W. Oertel, B. Mollenhauer, P. Wilmes (Esch-Sur-Alzette, Luxembourg)

    Objective: To search for molecular links between Parkinson’s disease (PD) pathogenesis and gut microbes based on integrated multi-omic analyses of fecal samples from patients with…
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