MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    In vivo relationship between synaptic density and functional connectivity in progressive supranuclear palsy: a multimodal [11C]UCB-J PET and resting state fMRI study.

    N. Holland, T. Rittman, T. Cope, A. Perry, S. Jones, G. Savulich, M. Malpetti, T. Fryer, F. Aigbirhio, J. O'Brien, J. Rowe (Cambridge, United Kingdom)

    Objective: To assess the relationship between synaptic density and functional connectivity in the primary tauopathy of Progressive Supranuclear Palsy (PSP). Background: PSP is a debilitating…
  • MDS Virtual Congress 2021

    Tinospora Cordifolia protects against Rotenone induced degeneration of dopaminergic neurons in mouse model of Parkinson’s disease

    S. Singh, H. Birla (Varanasi, India)

    Objective: To explore the neuroprotective mechanisms of T. cordifolia ethanolic extract against Rotenone (ROT)-intoxicated mouse model through proteomics approach. Background: The death of dopaminergic (DAergic)…
  • MDS Virtual Congress 2021

    The role of community engagement and involvement in Parkinson’s disease research: a case study from Africa

    N. Fothergill-Misbah, O. Thomas, H. Mwithiga, R. Walker (Newcastle Upon Tyne, United Kingdom)

    Objective: Using a case study from Africa to understand the potential role of community engagement and involvement (CEI) in future research on Parkinson’s disease (PD).…
  • MDS Virtual Congress 2021

    Does Macronutrient dietary Intake of patients with Parkinson disease correlates with the cognitive function (MoCA)?

    C. López Botello, S. Castillo Torres, I. Estrada Bellmann, B. Chávez Luevanos (Monterrey, Mexico)

    Objective: Analyze the correlation between macronutrient dietary intake and cognitive function of patients with Parkinson’s Disease Background: Several studies have shown that implementing a healthy…
  • MDS Virtual Congress 2021

    Movement disorders in demyelination: A case series of ten patients

    R. Singh, S. Pandey (New Delhi, India)

    Objective: To observe the association of various movement disorder with demyelinating disease. Background: Movement disorders in demyelinating diseases are not an unheard entity, but besides…
  • MDS Virtual Congress 2021

    Evaluating palliative care needs in patients with Parkinson’s disease and related disorders

    K. Kay, A. Killoran (Iowa City, USA)

    Objective: To assess the palliative care needs in patients with Parkinson’s disease and related disorders at an academic movement disorders clinic. Background: There is growing…
  • MDS Virtual Congress 2021

    The OASIS (OpicApone in Sleep dISorder) study in Parkinson’s disease: design and rationale of an open-label, single-arm, pilot trial

    R. Costa, C. Trenkwalder, J. Ferreira, D. Magalhães, J. Rocha, P. Soares-da-Silva (Coronado, Portugal)

    Objective: To evaluate the effects of opicapone (OPC) treatment on sleep disorders in patients with Parkinson’s disease (PD) and ‘wearing-off’. Background: OPC proved to be…
  • MDS Virtual Congress 2021

    Azathioprine immunosuppression and disease modification in Parkinson’s disease (AZA-PD): a randomised double-blind placebo-controlled phase II clinical trial

    J. Greenland, E. Cutting, S. Kadyan, S. Bond, A. Chhabra, C. Williams-Gray (Cambridge, United Kingdom)

    Objective: To design a clinical trial to test the concept that the immune system is integral in the progression of Parkinson’s disease (PD) and establish…
  • MDS Virtual Congress 2021

    Cinpanemab in Early Parkinson’s Disease: Phase 2 SPARK Study Results

    A. Lang, A. Siderowf, E. Macklin, W. Poewe, D. Brooks, H. Fernandez, O. Rascol, N. Giladi, F. Stocchi, C. Tanner, R. Postuma, D. Simon, E. Tolosa, B. Mollenhauer, M. Byrne, K. Fraser, J. Xiao, I. Sapir, J. Inra, R. Hutchison, M. Yang, T. Fox (Toronto, Canada)

    Objective: To evaluate cinpanemab (BIIB054) efficacy and safety. Background: Aggregated alpha-synuclein (α-syn), a major constituent of Lewy bodies, is thought to play a central role…
  • MDS Virtual Congress 2021

    Decreased expression of trace amines receptors on lymphocytes in Parkinson’s disease

    Z. Muruzheva, I. Ivleva, V. Maystrenko, O. Tumashova, M. Karpenko (Saint-Petersburg, Russian Federation)

    Objective: To determine the expression of TAAR1 and TAAR2 mRNA in leukocytes of patients with Parkinson's disease, depending on the stage of the disease and…
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