Clinical and genetic analysis of psychosis in Parkinson’s disease
Objective: This study aimed to examine the association of seven selected polymorphisms of DRD2, ANKK1, COMT and DAT genes with Parkinson’s disease psychosis (PDP) onset.…Axial Impairment Following Deep Brain Stimulation in Parkinson’s Disease: a Surgicogenomic Approach
Objective: We aimed to identify genetic variants associated with clinical heterogeneity in deep brain stimulation outcome of Parkinson’s Disease patients with an overall objective of…Correlating LRRK2 activation status in peripheral blood to urine BMPs in monogenic and idiopathic Parkinson’s disease
Objective: The greatest unmet need in Parkinson’s disease (PD) are disease-modifying treatments. The discovery of monogenic forms of PD has provided invaluable insights into pathomechanisms…Age-dependent multisystem parkinsonian features in a novel neuromelanin-producing transgenic mouse model
Objective: We aim to characterize the consequences of age-dependent intracellular neuromelanin accumulation in catecholaminergic neuronal populations to understand the relationship between this process and the…Interest of optical coherence tomography in Parkinson’s disease
Objective: To compare optical coherence tomography (OCT) results of retinal thickness (RT) and retinal nerve fiber layer (RNFLT) thickness of patients with idiopathic Parkinson's disease…Impaired interhemispheric synchrony in Parkinson’s disease patients with impulse control disorders
Objective: Our objective was to probe the significant role of lateralization in the pathogenesis of ICD. Background: Impulse control disorders (ICD) in Parkinson’s disease (PD) might…Feasibility study of diffusion tensor imaging fiber tracking in PD patients after DBS operation
Objective: To explore the feasible of depicting the nigrostriatal pathway (NSP), dentate rubro thalamic (DRTT) and hyperdirect pathway (HDP) for the postoperative PD patients with…Relationship of subcortical iron deposition and mitochondrial dysfunction in patients with idiopathic Parkinson’s disease
Objective: To investigate subcortical brain iron deposition as a potential predictor of the bioenergetic status in patients with idiopathic Parkinson's disease. Background: The underlying pathophysiology…Factors contributing to prefrontal cortical activity during walking and its response to dual-tasking in Parkinson’s disease
Objective: We examined the contribution of clinical, cognitive, and gait characteristics to prefrontal cortex (PFC) activity during walking and its response to dual-task in people…Slow wave activity as a marker of levodopa induced dyskinesia
Objective: To assess the role of slow wave activity during slow wave sleep (SWS-SWA) as a marker of levodopa induced dyskinesia (LID) development in Parkinson's…