Effects of white matter hyperintensities, neuropsychiatric symptoms, and cognition on activities of daily living: Differences between Dementia with Lewy Bodies and Alzheimer’s disease
Objective: To investigate if White matter hyperintensities (WMHs), neuropsychiatric symptoms and cognitive performance associate with, and/or predict activities of daily living (ADLs) differently in Alzheimer’s…Informant vs. Self-ratings of Activities of Daily Living in Parkinson’s Disease patients
Objective: To compare patient and informant ratings of impairments in activities of daily living (ADL) of Parkinson’s Disease (PD) patients. Background: Valid ratings of ADL…RELATION BETWEEN COGNITIVE INHIBITORY CONTROL AND ANTICIPATORY POSTURAL ADJUSTMENT DURING A CONFLICTUAL STEP INITIATION TASK IN PARKINSON’S DISEASE INDIVIDUALS.
Objective: Verify the association of inhibitory control on anticipatory postural adjustments (APA) during a conflictual step initiation task in individuals with Parkinson's disease (PD). Background:…Is cognitive performance related to motor performance among people with Parkinson disease?
Objective: To examine the relationship between cognitive and motor functioning among people with Parkinson disease (PD). Background: PD is a disabling, chronic condition affecting both…EIF4G1 gene variants in a family affected by Parkinson´s disease
Objective: Describe a novel mutation on a family affected by Parkinson´s disease. Background: 46 years old woman. She came to hospital complaining about tremor and…α-Synuclein in sympathetic nerve fibers distinguishes PRKN from LRRK2 and other genetic forms of Parkinson’s Disease
Objective: This cross-sectional observational study compared magnitudes of intra-neuronal deposition of α-synuclein in common and rare genetic forms of Parkinson’s disease. Background: Cytoplasmic inclusions of…Blood-based circulating microRNAs for discriminating between Parkinson’s disease subtypes
Objective: The aim of this study was to establish candidate blood miRNAs biomarkers for PD by comparing differences in miRNAs expression between distinct PD subtypes. Background: Blood…LIPAD (LRRK2/Luebeck) International Parkinson’s Disease Study: Protocol and feasibility study
Objective: To systematically assess clinical signs and symptoms including non-motor features, comorbidities, medication and environmental factors in 1,000 participants internationally: 300 with LRRK2 (Leucine-rich repeat…Fatty acids and Glucocerebrosidase activity as potential biomarkers of stearyl-CoA desaturase inhibition; an observational study of inter and intraday variation in healthy volunteers and patients with Parkinson’s disease
Objective: This study aimed to assess the naturally occurring levels and variation in plasma fatty acids (FA) and ceramide metabolism in healthy volunteers (HV) and…PD phenotype with premotor RBD is associated with a dysbiotic profile of gut microbiota.
Objective: The aim of the study was to compare the fecal microbial composition of a group of PD patients with and without premotor RBD. Background:…
