Remote assessment of prodromal Parkinson’s disease in a LRRK2 G2019S cohort
Objective: To compare remote application of the Movement Disorder Society (MDS) prodromal Parkinson’s disease (PD) criteria to expert clinical determination of possible parkinsonism in a…Integrated Multi-omics of the Gut Microbiome Reveal 2-Hydroxypyridine as a Novel Molecule Relevant to Parkinson’s Disease Pathogenesis
Objective: To search for molecular links between Parkinson’s disease (PD) pathogenesis and gut microbes based on integrated multi-omic analyses of fecal samples from patients with…Gut microbiota and nutritional profiles of Parkinson’s disease patients.
Objective: We investigated the gut microbiome (GM) composition in association with various clinical features and nutritional data in a large cross-sectional Australian Parkinson’s disease (PD)…Whole-transcriptome analysis of monocyte-derived macrophages from patients with Parkinson’s disease associated with mutations in the GBA gene
Objective: To understand specific molecular features of Parkinson’s disease associated with mutations in the GBA gene (GBA-PD), we analyzed the gene expression profile of peripheral-blood…DO FREEZING OF GAIT AND GAIT AUTOMATICITY IN PARKINSON’S DISEASE SHARE THE SIMILAR NEURAL SUBSTRATE?
Objective: To verify if freezing of gait (FOG) in Parkinson’s disease (PD) and gait automaticity share a similar neural substrate. Background: FOG in PD may…Insulin resistance and Parkinson’s disease
Objective: To investigate peripheral insulin resistance and cerebral FDG-PET changes in Parkinson’s disease (PD). Background: Glycated hemoglobin levels (HbA1c) is used as a marker of…Sex differences in brain and cognition in de novo PD patients
Objective: We aimed to investigate sex differences in brain atrophy and cognition in PD de novo patients through MRI subcortical volumetry and cortical thickness (CTh).…Constipation in Parkinson’s disease: Clinical and Neurosonographic Study
Objective: We aimed to study the possible impact of constipation on motor, non-motor, depressive symptoms, cognitive functions and neurosonographic findings in idiopathic Parkinson's disease (PD)…Neurofilament light is related to fractional anisotropy in early Parkinson’s diesease
Objective: We aimed to determine whether plasma NfL reflects changes in brain white matter integrity as measured using fractional anisotropy (FA) in patients with early…LFP spectral features associated with therapy complications in typical and early onset Parkinson’s disease
Objective: The aim of this study was to search for potential markers in the subthalamic nucleus activity of parkinsonian patients associated with levodopa-induced dyskinesias in…