α-synuclein and deficits of membrane trafficking in Parkinson’s Disease
Objective: Aim of the study is to understand the physical and functional relationships between the PD-associated protein α-synuclein and some of the Soluble N-ethylmaleimide-sensitive-factor Attachment…Perivascular spaces in the basal ganglia and long-term motor prognosis in newly diagnosed Parkinson’s disease
Objective: To investigate the association between enlarged perivascular spaces (PVSs) in the basal ganglia (BG-PVSs) and long-term motor outcomes in Parkinson’s disease (PD). Background: PVSs…Movement-related dynamics of β-γ phase-amplitude coupling in repetitive movement tasks of Parkinson disease
Objective: In this study, we aim to understand the functional role of β-γ phase amplitude coupling (PAC) during repetitive movement tasks and its relationship with…Clinical correlates of Parkinson’s disease metabolic pattern: not only a diagnostic tool
Objective: To define and cross-validate the glucose metabolism abnormalities related to Parkinson's Disease (PD), and to analyze pattern relationship with clinical phenotype Background: In PD,…Brain activity of the emotional circuit in Parkinson’s disease patients with freezing of gait
Objective: The aim of this observational study was to assess brain functional MRI (fMRI) activity during a “FoG observation task” in PD-FoG patients relative to…Analysis of brain structural connectivity networks and white matter integrity in patients with early Parkinson’s disease: a longitudinal study
Objective: The objective of this study was to analyze the differences in structural connectivity and white matter (WM) microstructural integrity in people with early-PD over…Neurophysiological features of the premotor cortex excitability parameters after a course of therapeutic transcranial magnetic stimulation in patients with Parkinson’s disease stage II living in the Zaporizhzhya region
Objective: Modern principles of Parkinson's Disease (PD) treatment don't include only pharmacotherapy, but also non-drug methods. Particularly, transcranial magnetic stimulation (TMS) is actively used in…High intensity exercise improves Sleep EEG Delta Power in Parkinson’s Disease
Objective: This novel study tests the hypothesis that 16 weeks of high-intensity exercise rehabilitation combining resistance training plus body-weight interval training, compared with a sleep…Locus coeruleus volume is reduced in Parkinson disease-related orthostatic hypotension.
Objective: To test whether structural pathology of the locus coeruleus (LC) is associated with orthostatic hypotension (OH) in Parkinson disease (PD). Background: OH is an…Intermittent theta burst stimulation over primary motor cortex ameliorates physical fatigue in Parkinson’s disease patients
Objective: To evaluate the effect of a single intermittent theta burst stimulation (iTBS) session on objective markers of physical fatigue of fatigue in patients with…
