A retrospective review of clinical features of Progressive Supranuclear Palsy (PSP) in a movement disorders clinic
Objective: Understanding the common clinical features of PSP. Background: PSP is a relatively rare progressive neurodegenerative disease, which can often be difficult to distinguish from…Coffee, smoking and aspirin are associated with age at onset and clinical severity in idiopathic Parkinson’s disease
Objective: To investigate a possible association between smoking, the consumption of caffeine and the use of aspirin on age at onset (AAO), motor and non-motor…Extensive volume increases sensitivity of alpha-synuclein accumulation in the gastrointestinal tract
Objective: This study aimed to verify whether evaluation of extensive tissue volume increases sensitivity of detecting alpha-synuclein (AS) pathology in the gastrointestinal (GI) tract in…Long-term cognitive and motor decline across the spectrum of Lewy body disease.
Objective: This study aims to compare the progression of motor and cognitive decline in dementia with Lewy bodies (DLB) compared with Parkinson’s disease (PD) using…AMP PD: Collaborating in the discovery of biomarkers to accelerate the development of therapies for Parkinson’s disease
Objective: The Accelerating Medicines Partnership in Parkinson’s Disease (AMP PD; https://amp-pd.org) aims to identify and validate diagnostic, prognostic, and progression biomarkers for Parkinson’s Disease (PD).…Motor skills of walking in Parkinson’s disease: towards a better understanding of the cognitive abilities implicated in F8WT.
Objective: to evaluate disease related and cognitive features involved in motor skills of walking in people with Parkinson’s disease (PWP). Background: curved path walking and…Sex-Specific White Matter Correlates of Neuropsychological Measures in Parkinson’s disease with Mild Cognitive Impairment
Objective: To identify sex-specific white-matter (WM) correlates of neuropsychological measures in Parkinson’s disease (PD) with mild cognitive impairment (MCI). Background: Neuropsychological measures of executive function…A prospective study of Parkinson’s disease progression towards dementia – dynamics and defining motor features
Objective: Our goal was to investigate the rate of progression to dementia (PDD) in our cohort of Parkinson’s disease (PD) patients and to explore how…Genotypic and phenotypic spectrum of PINK-1 associated parkinsonism in 44 mutation carriers from 11 Tunisian families
Objective: To characterize the family history and clinical features of mutations of the PINK-1 gene in a cohort of Tunisian patients with Parkinson disease (P.D)…Rare Neurodegenerative Phenotypes in Patients Carrying Homozygous GBA1 Mutations
Objective: To describe patients with Type 1 Gaucher disease who developed a rare neurodegenerative disease other than synucleinopathies. Background: Lysosomal dysfunction as a contributor to…
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