A French national multicentric prospective study of the 1-year impact of STN-DBS on speech in Parkinson’s disease: profile of progression and prognostic factors.
Objective: 1) To describe the evolution of speech in a large cohort of patients before and 1 year after STN-DBS. 2) To search for preoperative…Comparative Effectiveness of Carbidopa/Levodopa Enteral Suspension and Deep Brain Stimulation on Pill Burden Reduction in Medicare Patients With Advanced Parkinson’s Disease
Objective: To evaluate real-world comparative effectiveness of Carbidopa/Levodopa Enteral Suspension (CLES) versus Deep Brain Stimulation (DBS) initiation on pill burden reduction in patients with Advanced…Inhibition of GluN2D-containing NMDA receptors alleviates the loss of dopaminergic neurons and behavioral deficits in 6-OHDA-induced model of Parkinson’s disease
Objective: The aim of this study is to explore whether the inhibition of GluN2D-containing NMDA receptors (NMDAR2D) can delay the pathological manifestations of Parkinson's disease…Longitudinal 18F-PBR06 (TSPO) and Volumetric MR Imaging as Pharmacodynamic Endpoints for MSA – Ongoing Investigator Sponsored Trial of Verdiperstat
Objective: In multiple system atrophy (MSA) patients to: 1) evaluate 18F-PBR06 positron emission tomography (PET) for longitudinal assessment of 18-kilodalton-translocator protein (TSPO) binding; 2) assess…Neuroimaging associations to gait impairments in progressive supranuclear palsy
Objective: The aim of this study was to determine how multimodal imaging biomarkers were related to abnormalities in three-dimensional motion-based gait and balance measurements in…The pandemic stress impact on disease progression in COVID-19 seronegative patients with idiopathic Parkinson’s Disease.
Objective: To investigate the impact of chronic stress (CS) induced by the present pandemic on the progression rates of motor and cognitive impairment, on neuro-inflammatory…Could Gender have an effect on Clinical and Transcranial Parenchymal Ultrasound Findings in Parkinson’s disease Patients?
Objective: We aimed to explore the possible differences between males and females as regarding motor, non-motor, depressive symptoms, cognitive functions and Transcranial Parenchymal Ultrasound (TCS)…Investigation of the consultation status and clinical symptoms of patients with Parkinson’s disease after the spread of COVID-19
Objective: This study investigated the consultation status and clinical symptoms of patients with Parkinson’s disease (PD) after the coronavirus disease 2019 (COVID-19) pandemic. Background: Due…Central and Peripheral neurological manifestations of COVID-19 in a cohort of patients with Parkinson’s disease.
Objective: To describe central and peripheral neurological manifestations in patients with COVID-19 and Parkinson’s disease. Background: COVID-19 is associated with central and peripheral neurological manifestations.…The dual cognitive syndrome in Parkinson’s disease: a resting-state functional connectivity study
Objective: To assess resting-state functional connectivity modifications characterizing the frontostriatal and posterior cortical cognitive subtypes in Parkinson’s Disease (PD) Background: The dual syndrome hypothesis (Kehagia…
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