Hyposmia as a biomarker in patients with Parkinson’s disease and atypical Parkinsonism
Objective: To investigate neural correlates associated with olfactory dysfunction using fMRI and EEG in Parkinsonism. Background: Patients with Parkinsonism experience non-motor symptoms during the onset…Levodopa-induced dyskinesias and substantia nigra dopamine D3 receptor availability in Parkinson’s disease
Objective: To investigate with PET and the radioligand [11C]PHNO whether levodopa-induced dyskinesias in Parkinson disease (PD) are associated with dopamine-D3 receptor (D3R) overexpression in substantia nigra…Application of substantia nigra feature extraction in the progression of Parkinson’s disease based on magnitude image of susceptibility weighted imaging
Objective: This present study was aimed to investigate the potential value of the substantia nigra (SN) radiomic feature for the prediction of PD progression. Background:…Impairment of the mesocortical dopamine system in Parkinson’s disease patients with freezing of gait in a multimodal imaging approach
Objective: To investigate the involvement of dopaminergic systems in Parkinson’s disease (PD) patients with freezing of gait (FOG) using a multimodal assessment involving 18 F-DOPA-PET…Functional connectivity and volumetric data improve prediction of DBS outcomes
Objective: To determine the clinical utility of neuroimaging markers to predict motor outcomes for deep brain stimulation (DBS) of the subthalamic nucleus (STN) in Parkinson…Rhythmic activity of subthalamic neurons during externally and internally generated movements in Parkinson’s disease
Objective: To find the specificity of neuronal responses in the subthalamic nucleus during externally and internally generated voluntary movements in Parkinson’s disease. Background: The motor…Genetic Profiling of Early Synucleinopathy in Rat Nigrostriatal Dopamine Neurons
Objective: Identification of changes in gene expression in rat nigral neurons associated with early phases of synucleinopathy. Background: Early phases of synucleinopathies such as Parkinson’s…Progression in Parkinson’s disease: Variation in motor and non-motor symptoms severity and predictors of decline in cognition, motor function, incapacity and Health Related Quality of Life
Objective: Assess the progression of motor and non-motor symptoms in Parkinson's Disease (PD) and predictors of cognitive, motor, activities of daily living (ADL) and Health…Is the Montreal Cognitive Assessment (MoCA) Suitable for Identifying Mild Cognitive Impairment in Parkinson’s Disease?
Objective: To explore neuropsychological test scores of Parkinson’s disease (PD) patients who were categorized based on their Montreal Cognitive Assessment (MoCA) scores as having mild…Does constipation predict cognitive impairment and dementia in de novo Parkinson’s disease patients? A multi-cohort longitudinal data analysis
Objective: To investigate if constipation predicts the development of cognitive impairment (CI) and dementia in de novo Parkinson’s disease (PD). Background: Constipation is one of…
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