Long-term effect of deep brain stimulation in a monkey model of Parkinson’s disease with L-Dopa–induced dyskinesias
Objective: This study investigated the effect of long-term deep brain stimulation (DBS) of the subthalamic nucleus (STN) on motor behavior in a parkinsonian monkey treated…Reliability and Stability of Programming Directional Deep Brain Stimulation
Objective: To determine the reliability and stability of programming directional deep brain stimulation (d-DBS) systems. Background: Conventional omni-directional deep brain stimulation (o-DBS) of the subthalamic…Use of a new Stimulation Field Visualization Tool in Parkinson’s Disease Subjects Treated with Subthalamic Nucleus Deep Brain Stimulation (sub-analysis from INTREPID RCT)
Objective: To describe the location of stimulation fields as applied to optimized programming parameters in a cohort of STN DBS PD patients participating in INTREPID…Assessment of Real World Effectiveness: A Deep Brain Stimulation Retrospective Outcomes Study
Objective: To report the real-world clinical outcomes of patients utilizing deep brain stimulation (DBS) to manage symptoms of Parkinson's disease, dystonia, and Essential tremor. Background:…Automatic classification of abnormal movement in Huntington’s disease using wearable sensors and machine learning
Objective: To integrate wearable sensors into brief clinical assessments and use machine learning to infer HD disease status and predict UHDRS motor subscores for specific…Smartphone-based context awareness to improve ambulatory Parkinson’s monitoring
Objective: To determine the utility of context-awareness algorithms based on sensors in smartphones to improve ambulatory Parkinson’s disease (PD) monitoring. Background: Previous research shows that optimal motion sensor-based ambulatory PD monitoring requires multiple sensors to…Clinical and kinematic assessment of a glove-based tremor dampener in patients with essential tremor
Objective: To determine the effectiveness of a biomechanical glove in the setting of essential tremor (ET) using both kinematic and clinical evaluation. Background: Essential tremor…The Unique Voiceprint Changed In Parkinson’s Disease
Objective: To discover the unique voiceprint changed in patients with Parkinson’s disease. Background: Parkinson’s disease, PD, is a serious neurodegenerative disease affected millions old people…Intravenous Immunoglobulin Treatment did not improve Tics in a Patient with Gilles de la Tourette Syndrome and intrathecal Antibody Synthesis
Objective: Here we present the unique case of a female patient with GTS, who not only exhibited intrathecal antibody synthesis documented by positive OCBs, but…Altered Spontaneous Brain Activity in Essential Tremor with and without Resting Tremor: A Resting-state fMRI Study
Objective: This study aims to use resting-state functional magnetic resonance imaging (rs-fMRI) to explore the alterations of brain activity in drug-naïve patients with Essential tremor…
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