Serum microRNA-29 family as potential biomarkers for cognitive impairment in Parkinson’s disease
Objective: To examine whether miRNA-29s (miR-29s) in serum could be used as biomarkers for either Parkinson’s disease with dementia (PDD) or Parkinson’s disease with mild…Longitudinal Measurements of Glucocerebrosidase activity in Parkinson’s patients and controls: the PPMI study
Objective: To test the correlations between longitudinal measurements of glucocerebrosidase (GCase; encoded by GBA) enzymatic activity and Parkinson’s disease (PD) phenotype in the Parkinson’s Progression…A Fluctuating Qualitative Dermatoglyphic Trait, Dankmeijer’s and Furuhata’s Index as a Risk Marker in Diabetic Parkinson’s Patients of Guyana: A Case-Control Study
Objective: The current study aims to compare and evaluate the fluctuating qualitative dermatoglyphic trait, Furuhata’s and Dankmeijer’s index as a risk marker in Diabetes and…Neurodevelopmental disorder and parkinsonism in a patient with WDR45 variant: a long-term outcome
Objective: To expand the clinical spectrum of WDR45 deficiency. Background: Beta-propeller protein-associated neurodegeneration (BPAN) due to WDR45 defect is a rare X-linked dominant disorder of…Burden of variants in Parkinson’s disease-associated genes in GBA mutation carriers
Objective: The main objective of this study is to examine the burden of variants in genes that are known or suspected to be involved in…Multiplex biomarker discovery for diagnostic and progression markers for Parkinson’s disease with the proximity extension assay technology on inflammation-related analytes
Objective: To identify diagnostic and progression biomarkers in the longitudinal DeNoPa cohort of (at enrolment) de novo Parkinson’s disease (PD) and healthy controls (HC) using…L-DOPA treatment in N2a cells stimulates neuromelanin biosynthesis: Using a novel in vitro model to examine the effect of iron and light on neuromelanin production
Objective: Naturally-occuring quantities of in vivo neuromelanin (NM) are low, and the collection of NM from tissue involves laborious extraction and isolation. Thus, in vitro…The feasibility of detailed phenotyping of muscle mitochondrial respiratory chain function and content in Parkinson’s disease
Objective: We aimed to determine: 1) the feasibility of obtaining and characterising skeletal muscle; and 2) if muscle mitochondrial respiratory chain (MRC) function and content…Sex differences on dynamic functional connectivity in Parkinson’s disease and healthy controls
Objective: The main objective was to evaluate the influence of sex in time-varying functional connectivity (FC) characteristics in Parkinson’s disease (PD) patients and healthy adults…Magnetic Property Characterization of Deep Gray Matters in Patients with Alzheimer’s diseases, Dementia with Lewy Bodies and Parkinson’s Disease Dementia using Quantitative Susceptibility Mapping
Objective: The purpose of this study was to characterize magnetic properties of deep gray matters in Alzheimer's diseases (AD), dementia with Lewy bodies (DLB) and…
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