Regional free-water differentially associated with glial activation, neuroinflammation, and neurodegeneration in de novo Parkinson’s disease
Objective: Assess to what extent free-water(FW) as measured by diffusion-weighted MRI(dMRI) is a neuroimaging marker of glial activation, neuroinflammation, and neurodegeneration in de novo Parkinson’s disease(PD) patients from…Deficient Balance Mechanisms during Walking in People with Parkinson’s Disease
Objective: Investigate whether people with Parkinson’s disease (PD) have deficient balance mechanisms following visual perturbations during walking. Background: We recently showed that maintaining upright balance…Rhythmic movements decompose in Parkinson’s disease with worse disease severity at low frequencies: akinesia or impaired ability to move more slowly than comfortable?
Objective: To explore the relationship between disease severity, minimum comfortable velocity and dwell time in Parkinson's disease. Background: People find it hard to move smoothly…The dysfunctional autonomic function and “dysfunctional” fatigue in drug naïve Parkinson’s disease
Objective: In the present study, the relationship between fatigue and autonomic dysfunction in drug-naïve PD patients was investigated. Background: Fatigue is a common and disabling…Loss of Weight Associated with Levodopa / Carbidopa Intestinal Gel
Objective: To define the prevalence and severity of WL in patients of the Movement Disorders Unit of our center treated with LCIG and to analyze…Prevalence of apathy in Indian patients with Parkinson’s disease and its correlation with nigrosomal imaging
Objective: To assess the prevalence of apathy in patients with patients with Parkinson's disease and to correlate it with nigrosomal imaging in a subset of…Is acoustic speech analysis applicable for evaluation of swallowing impairment in patients with Parkinson’s disease (PD)?
Objective: More than 80% of patients with Parkinson’s disease develop dysphagia during the course of the disease. Methods considered as ‘gold standard’ in swallowing evaluation…Effects of Co-Morbidities on Sleep Patterns in Parkinson’s Disease: A Study of 84 Ibadan Patients
Objective: To assess the effects of co-morbidities on sleep patterns in PD. Background: Parkinson’s disease is a progressive neurodegenerative disease. The non-motor symptoms are said…The non-declaration of musculoskeletal pain in Parkinson’s disease in patient-related outcome measures –The King’s experience
Objective: To determine the usefulness of patient related outcome (PRO) measures in highlighting non-declaration of pain, a challenging non-motor symptom (NMS) of Parkinson’s disease (PD).…Dysphasia as a novel approach for classification of speech disorders in Parkinson’s disease and other forms of neurodegeneration
Objective: To classify and identify the features of speech disorders in Parkinson's disease and other neurodegenerative diseases. Background: No unified approach to classification and diagnostics…
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