Directional versus conventional subthalamic deep brain stimulation for advanced Parkinson’s disease: Short-term outcomes of a pilot study
Objective: To investigate efficacy of STN-DBS via segmented directional leads compared to conventional omnidirectional leads in PD-patients. Background: Recently, novel leads which allow stimulation steering in…Establishment of a Visual Analog Scale (VAS) for DBS Programming (VISUAL – STIM Trial)
Objective: With this study, we wanted to demonstrate a new strategy to adjust stimulation parameters and lead configurations, using a visual analog scale. Background: Deep brain…Neuropathological Changes Following PPN Region DBS
Objective: To examine neuropathological changes surrounding deep brain stimulation (DBS) electrode in pedunculopontine nucleus (PPN) region. Background: Freezing of gait (FOG) in Parkinson’s disease (PD)…Remote monitoring of physical activity and falls in patients with Huntington’s disease using wearable sensors
Objective: To investigate the use of a novel tele-health system to remotely monitor physical activity and falls in patients with Huntington’s disease. Background: Increased physical…Not so simple: the challenge of developing a non-motor symptoms app (NMS Assist) for people with Parkinson’s (PwP)
Objective: To evaluate usability and identify the challenges for PwP when using NMS Assist. Background: There is great potential for mHealth technologies, such as apps,…Instrumented Detection of Fluctuations with Wearable Devices in Parkinson’s Disease
Objective: The objective of this study is to evaluate the efficacy in fluctuations detection of a system consisting of wearable devices embedding Inertial Measurement Units…Wearable sensors: a real-world characterization of Parkinson’s disease
Objective: To develop and validate new outcome measures of Parkinson's disease (PD) using wearable sensors (MC10, BioStamp nPoint®) in a natural history study of four…Cerebellar structural covariance networks in young people with Tourette syndrome
Objective: To investigate discrete structural brain networks in children and adolescents with Tourette syndrome [TS] relative to a group of matched control participants. Background: TS…Efficacy and safety of CX-8998 in T-CALM, a randomized, double-blind, placebo-controlled, phase 2a trial in participants with essential tremor: subgroup analysis by baseline tremor severity
Objective: Evaluate efficacy and safety of CX-8998 in essential tremor (ET) as a function of baseline tremor severity. Background: CX-8998, a selective modulator of T-type…Essential tremor and essential tremor plus are essentially similar on electrophysiological tremor analysis
Objective: To compare the electrophysiological characteristics of tremor in subjects with Essential Tremor (ET) and Essential Tremor Plus (ET Plus). Background: Patients with neurological signs…
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