Multimodal EEG-MRI based machine learning model in identifying Parkinson’s disease with mild cognitive impairment
Objective: To evaluate the diagnostic value of quantitative electroencephalogram (qEEG) and structure Magnetic resonance (sMR) in identifying mild cognitive impairment in Parkinson’s disease (PD-MCI) via…Moderately frequent and private variants in PRKN are associated with late-onset Parkinson’s disease
Objective: We hypothesized that heterozygosity for rare coding variants in PRKN, PINK1 or PARK7 might also represent a risk factor for sporadic late-onset PD.[4] Background:…Association of Interleukin (IL)-2 and IL2RA gene polymorphisms with Parkinson’s disease in Taiwan
Objective: The purpose of this study is to investigate if interleukin 2 (IL-2) and interleukin 2 receptor alpha (IL2RA) genes are associated with Parkinson’s disease…Educating Spanish-Speaking Communities about Parkinson’s, Research Participation and Genetics: A Community Health Worker (Promotores) Model For Outreach
Objective: To prepare promotores to educate Spanish-speaking communities about Parkinson’s disease (PD), research participation and genetics. Background: Hispanic PD communities are less likely to see a specialist and are underrepresented…GCH1 variants contribute to risk and earlier age at onset in Parkinson’s disease
Objective: Our aim was to identify the potential role of known genetic components of GCH1, including rare and common variants in coding and non-coding regions,…miRNA sequencing from routine colonic biopsies reveals an enrichment of submucosal hsa-miRNA-486-5p in Parkinson’s disease
Objective: In the present work, we aimed to investigate the expression of microRNAs (miRNAs) in routine colonic biopsies obtained from patients with idiopathic Parkinson's disease…Protective role of astrocytes on α-synuclein accumulation and propagation
Objective: This study is aimed to investigate the role of astrocytes on the accumulation and propagation of α-synuclein (a-syn), the main component of Lewy bodies/neurites,…Intrinsic brain functional connectivity predicts treatment-related motor complications in drug-naive Parkinson’s disease patients
Objective: Using resting-state functional MRI, we investigated intrinsic brain networks connectivity at baseline in a cohort of drug-naïve Parkinson’s disease (PD) patients which successively developed treatment-related…Pattern of cerebral perfusion in early de novo Parkinson’s disease with mild cognitive impairment using voxel-based analysis of 3D arterial spin-labeling imaging
Objective: We aimed to investigate the patterns of cerebral perfusion in early de novo Parkinson’s disease (PD) patients with different cognitive states and to determine…Sex-specific white matter alterations in Parkinson’s disease with mild cognitive impairment
Objective: Whether diffusion MRI (dMRI)-derived measures might help to understand sex-specific alterations of white-matter (WM) changes in Parkinson’s disease (PD) patients, with and without mild…
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