Glucocerebrosidase Deficiency Mediates Propagation of Protein Aggregation via Extracellular Vesicle Dysregulation
Objective: Investigate a role for GBA in accelerating the spread of protein aggregates via extracellular vesicles (EVs). Background: Parkinson’s disease (PD) progression correlates with temporo-spatial…A novel peptide reduces α-synuclein levels and neurodegeneration in cell, invertebrate, and mammalian models of Parkinson’s disease
Objective: To identify and test the effectiveness of a novel peptide to reduce α-synuclein levels and neurodegeneration in cell and animal models of Parkinson’s disease…Diagnostic value of vagus nerve ultrasound in Parkinson’s disease
Objective: To detect by the ultrasound (US) the possible presence of vagus nerve atrophy in patients with PD and its relation to severity of motor,…Altered interhemispheric synchrony in Parkinson’s disease patients with levodopa-induced dyskinesias
Objective: Our investigation aimed to explore interhemispheric functional alterations and its corresponding morphological synchronization changes. Background: Levodopa-induced dyskinesias are common motor complication of Parkinson’s disease…Disrupted functional brain connectome at the early non-freezing stage of Parkinson’s disease patients with freezing of gait
Objective: To investigate topological organization of the functional brain connectome at the early non-freezing stage of Parkinson’s disease (PD) patients with freezing of gait (FOG).…Look Again: The Diagnostic Value of Repeat Dopamine Transporter Imaging
Objective: To demonstrate value and clinical significance of repeated and longitudinal 123I-FP-CIT SPECT dopamine transporter imaging (DaTscan) with quantitative data analysis for clinical use. Background:…Impulse control disorders in Parkinson’s disease: A whole brain morphometric and diffusion tensor study
Objective: To study morphometric and structural connectivity changes in the mesocorticolimbic pathway associated with the occurrence of impulse control disorders in Parkinson's disease. Background: Impulse…Quantitative Evaluation of Iron Content in Idiopathic Rapid Eye Movement Sleep Behavior Disorder
Objective: The aim of this study was to quantitatively evaluate iron content in idiopathic rapid eye movement sleep behavior disorder patients using quantitative susceptibility mapping.…Effect of globus pallidus interna deep brain stimulation on functional connectivity in patients with Parkinson’s disease
Objective: To elucidate the effect of deep brain stimulation at globus pallidus interna (GPi-DBS) on the functional brain network of patients with Parkinson's disease (PD).…Visual Motion Perception and Metacognition in Parkinson’s disease
Objective: To investigate visual motion perception as a potential contributor to impaired visual self-motion perception in PD. To measured metacognitive ability and bias in PD…
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