Deep learning-based automatic nigrosome 1 segmentation on 3T susceptibility-weighted MRI
Objective: The aim of this study was to develop a deep learning-based system for automatic nigrosome 1 segmentation on susceptibility-weighted imaging (SWI) from 3T magnetic…MRI functional connectivity analysis for speech impairment in Parkinson’s disease
Objective: We aimed to investigate underlying modifications of MRI functional connectivity between dysarthric and non-dysarthric patients with Parkinson’s disease and healthy controls. Background: Altered speech…Alterations in functional networks contribute to depression in Parkinson’s disease: A resting-state functional magnetic resonance imaging study
Objective: The aim of this research was to investigate alterations in functional brain networks in PD patients with depression (DPD) and their association with demographic…Cortical thickness and volume to automatically identify Parkinson’s patients using SVM
Objective: With this work, we aim to automatically classify patients with Parkinson’s disease (PD) and controls, only on the basis of neuroimaging parameters. Background: Dysfunctions…Microstructural changes in GBA mutation carriers with depression
Objective: To investigate structural changes associated with depression in glucocerebrosidase (GBA) mutation carriers. Background: Depression is a common non-motor symptom in Parkinson’s disease (PD); however,…Rate of Neuromuscular Excitation during Cycling Related to Mobility in Parkinson’s Disease
Objective: Aim 1 was to compare rates of neuromuscular excitation during cycling at maximum pedaling speeds between people with Parkinson’s disease (PD) who are fast…Somatosensory temporal discrimination threshold improves after unilateral HIFU subthalamotomy in asymmetrical PD
Objective: To compare somatosensory temporal discrimination threshold (STDT) in both body sides previously and 4 months after unilateral high intensity focused ultrasound (HIFU) subthalamotomy of…The role of dopamine mis-metabolism in preclinical Parkinson’s disease olfactory deficits
Objective: To gain an understanding of the underlying pathological mechanisms of Parkinson’s disease (PD)-related hyposmia using post-mortem human olfactory bulbs and an in vivo model…Serum molecular markers and non-motor symptoms in Parkinson’s disease
Objective: The aim of this study was to examine the association between several serum molecular markers and different measures of non-motor symptom burden in PD.…Poor Sleep Quality is Associated With Fatigue in Early Parkinson’s Disease: A Longitudinal Study in the Early Parkinson’s Disease Longitudinal Singapore Study (PALS) Cohort
Objective: This study aims to explore the associations between baseline sleep quality and the progression of other non-motor symptoms in early Parkinson’s disease (PD). Background:…
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