A retrospective analysis of multicenter brain signal data recorded in Parkinson’s subjects implanted with deep brain stimulation leads
Objective: To assess the prevalence and factors of detectable local field potential (LFP) signals in the subthalamic nucleus (STN) of Parkinson’s disease (PD) patients. Background:…Varenicline for the Treatment of Postural and Gait Dysfunction in Parkinson’s Disease
Objective: To determine if varenicline is effective for balance in Parkinson’s disease (PD). Background: Incidence of falls resulting from imbalance is estimated at 68% for…Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Impact on Dyskinesia
Objective: Assess impact of apomorphine sublingual film (APL-130277; APL) on time spent with and functional impact of dyskinesia among patients with Parkinson’s disease (PD) and…Serious games home rehabilitation program to treat gait and balance disorders in patients with Parkinson’s disease: A randomised controlled trial
Objective: To test the efficacy of an exergame rehabilitation programme at home to treat dopa-resistant gait and balance disorders in Parkinson’s disease (PD) patients. Background:…Directional versus Omnidirectional Deep Brain Stimulation: Results of a Multicenter Prospective Blinded Crossover Study
Objective: To compare the range of stimulation amplitudes that can relieve symptoms without side effects, between directional and omnidirectional DBS. Background: Published reports on directional…Budget Impact of Apomorphine Sublingual Film for On-Demand Treatment of Patients With Parkinson’s Disease and “OFF” Episodes
Objective: To estimate the budget impact of introducing apomorphine sublingual film (APL-130277; APL) as an on-demand treatment for patients with Parkinson’s disease (PD) and “OFF”…Super-Responders to Opicapone Adjunct Treatment to Levodopa in Parkinson’s Disease Patients with Motor Fluctuations: Combined Post-Hoc Analysis of BIPARK-I and II
Objective: To evaluate the efficacy and safety of opicapone (OPC) in Parkinson’s disease (PD) patients who were considered ‘super-responders’ (>= 2 hours of OFF-time reduction…Non-pharmacological Treatment for Parkinson’s Disease Patients with Depression: A Meta-analysis of Repetitive Transcranial Magnetic Stimulation and Cognitive-Behavioral Treatment
Objective: This meta-analysis aims to assess the effect of non-pharmacological treatments for depression in patients with PD. Background: Antidepressants are the mainstay of treatment for…Novel walker attachment for gait dysfunction in Parkinson’s disease: Case report
Objective: To describe a patient with advanced PD who noted improved balance and fewer falls while using a novel belt attachment for his assistive device.…Ceftriaxone improves motor function in a rat hemi-parkinsonian model: Potential to delay bilateral progression of motor deficits in Parkinson’s disease
Objective: This study sought to evaluate the impact of ceftriaxone, as a potential repurposed drug, in ameliorating motor decline in a unilateral rat 6-hydroxydopamine (6-OHDA)…
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